Evidence map›Paper›PMID 35971866›Full record

ArticleEuropean journal of neurology2022

European Neuromuscular Centre consensus statement on anaesthesia in patients with neuromuscular disorders.

Luuk R van den Bersselaar, Luc Heytens, Helga C A Silva, Jens Reimann, Giorgio Tasca, Óscar Díaz-Cambronero, Nicoline Løkken, Anna Hellblom, Philip M Hopkins, Henrik Rueffert and 12 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in European journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Comprehensive Review of Anesthetic Strategies for Patients With Neurodegenerative Diseases.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  7. Atrial arrhythmia ablation in myotonic muscular dystrophy patients: a single institution experience.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Review
  15. Article
  16. Article
  17. Review
  18. A Review of Muscular Dystrophies.Anesthesia progress · 2024
    Review
  19. Review
  20. The congenital muscular dystrophies.Annals of the Child Neurology Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 19 institutions in 14 countries.

Luuk R van den BersselaarMalignant Hyperthermia Investigation Unit, Department of Anaesthesiology, Canisius Wilhelmina Hospital Nijmegen, Nijmegen, The Netherlands.ORCID 0000-0001-7735-3267
Luc HeytensMalignant Hyperthermia Research Unit, Departments of Anaesthesiology and Neurology, University Hospital Antwerp, University of Antwerp and Born Bunge Institute, Antwerp, Belgium.
Helga C A SilvaMalignant Hyperthermia Unit, Department of Surgery, Discipline of Anaesthesia, Pain, and Intensive Care, São Paulo Federal University, São Paulo, Brazil.
Jens ReimannDepartment of Neurology, University of Bonn Medical Centre, Bonn, Germany.ORCID 0000-0003-3349-6877
Giorgio TascaUOC of Neurology, A. Gemelli University Polyclinic Foundation, Scientific Institute for Research and Health Care, Rome, Italy.ORCID 0000-0003-0849-9144
Óscar Díaz-CambroneroMalignant Hyperthermia Unit, Department of Anaesthesiology, Perioperative Medicine Research Group, La Fe University and Polytechnic Hospital, Valencia, Spain.
Nicoline LøkkenCopenhagen Neuromuscular Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Anna HellblomDepartment of Intensive and Perioperative Care, Skåne University Hospital Lund, Lund, Sweden.
Philip M HopkinsLeeds Institute of Medical Research at St James's, University of Leeds and Malignant Hyperthermia Investigation Unit, St James's University Hospital, Leeds, UK.
Henrik RueffertSchkeuditz Helios Clinic, Malignant Hyperthermia Investigation Unit, Department of Anaesthesiology, Intensive Care, Pain Therapy, University Hospital Leipzig, Leipzig, Germany.
Börge BastianSchkeuditz Helios Clinic, Malignant Hyperthermia Investigation Unit, Department of Anaesthesiology, Intensive Care, Pain Therapy, University Hospital Leipzig, Leipzig, Germany.
Juan Jesus VilchezNeuromuscular Centre, La Fe Hospital UIP and ERN EURO-NMD, Neuromuscular Research Group at La Fe IIS and CIBERER, Valencia, Spain.ORCID 0000-0002-0532-2872
Robyn GilliesMalignant Hyperthermia Diagnostic Unit, Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Stephan JohannsenDepartment of Anaesthesiology, Intensive Care, Emergency, and Pain Medicine, Centre for Malignant Hyperthermia, University Hospital Würzburg, Würzburg, Germany.
Francis VeyckemansPaediatric Anaesthesia Clinic, Jeanne de Flandre Hospital, Lille University Hospital Centre, Lille, France.
Tino MuensterDepartment of Anaesthesia and Intensive Care Medicine, Hospital of the Order of St John of God, Regensburg, Germany.
Andrea KleinDepartment of Paediatric Neurology, University Children's Hospital UKBB, Basel, Switzerland.
Ron LitmanDepartment of Anaesthesiology and Critical Care, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Heinz JungbluthDepartment of Paediatric Neurology, Neuromuscular Service, Evelina's Children Hospital, Guy's and St Thomas' Hospital National Health Service Foundation Trust, London, UK.ORCID 0000-0002-7159-3427
Sheila RiaziMalignant Hyperthermia Investigation Unit, Department of Anaesthesiology and Pain Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Nicol C VoermansDepartment of Neurology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands.
Marc M J SnoeckMalignant Hyperthermia Investigation Unit, Department of Anaesthesiology, Canisius Wilhelmina Hospital Nijmegen, Nijmegen, The Netherlands.
Helios Park-Klinikum Leipzig · DEHospital Universitari i Politècnic La Fe · ESRadboud University Nijmegen · NLCanisius-Wilhelmina Ziekenhuis · NLChildren's Hospital of Philadelphia · USCopenhagen University Hospital · DKHôpital Jeanne de Flandre · FRInstitute for Scientific Interchange · ITNational Health Service · GBSkåne University Hospital · SESt John of God Hospital · AUThe Royal Melbourne Hospital · AUUniversidade Federal de São Paulo · BRUniversitätsklinikum Würzburg · DEUniversity Health Network · CAUniversity of Antwerp · BEUniversity of Bern · CHUniversity of Bonn · DEUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePatients with neuromuscular conditions are at increased risk of suffering perioperative complications related to anaesthesia. There is currently little specific anaesthetic guidance concerning these patients. Here, we present the European Neuromuscular Centre (ENMC) consensus statement on anaesthesia in patients with neuromuscular disorders as formulated during the 259th ENMC Workshop on Anaesthesia in Neuromuscular Disorders.

methodsInternational experts in the field of (paediatric) anaesthesia, neurology, and genetics were invited to participate in the ENMC workshop. A literature search was conducted in PubMed and Embase, the main findings of which were disseminated to the participants and presented during the workshop. Depending on specific expertise, participants presented the existing evidence and their expert opinion concerning anaesthetic management in six specific groups of myopathies and neuromuscular junction disorders. The consensus statement was prepared according to the AGREE II (Appraisal of Guidelines for Research & Evaluation) reporting checklist. The level of evidence has been adapted according to the SIGN (Scottish Intercollegiate Guidelines Network) grading system. The final consensus statement was subjected to a modified Delphi process.

resultsA set of general recommendations valid for the anaesthetic management of patients with neuromuscular disorders in general have been formulated. Specific recommendations were formulated for (i) neuromuscular junction disorders, (ii) muscle channelopathies (nondystrophic myotonia and periodic paralysis), (iii) myotonic dystrophy (types 1 and 2), (iv) muscular dystrophies, (v) congenital myopathies and congenital dystrophies, and (vi) mitochondrial and metabolic myopathies.

conclusionsThis ENMC consensus statement summarizes the most important considerations for planning and performing anaesthesia in patients with neuromuscular disorders.

Indexed as

AnesthesiaAnestheticsMuscular DiseasesNeuromuscular DiseasesNeuromuscular Junction DiseasesChildHumansAnestheticsanaesthesiamalignant hyperthermiamyopathyneuromuscular disordersperioperative care

Identifiers

PMID35971866
PMCPMC9826444
OpenAlexW4292186445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.