Evidence map›Paper›PMID 35971763›Full record

ArticleJournal of Korean medical science2022

Operational Definition Identifying Osteoporotic Vertebral Fractures in the Claims Database.

Min Heui Yu, Namki Hong, Seunghyun Lee, Ha-Young Kim, Hye-Sun Park, Sang-Min Park, Young-Kyun Lee, Tae-Young Kim, Yong-Chan Ha, Yumie Rhee and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Diabetes progression and its association with fracture risk in type 2 diabetes.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
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  6. Differential fracture risk in breast cancer patients based on endocrine therapy and age: a nationwide cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  7. Article
  8. Article
  9. Association between dental diseases and oral hygiene care and the risk of vertebral fracture: a nationwide cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Min Heui Yu *Department of Internal Medicine, Endocrine Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3787-795X
Namki Hong *Department of Internal Medicine, Endocrine Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8246-1956
Seunghyun LeeDepartment of Internal Medicine, Yonsei Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0001-9254-183X
Ha-Young KimDepartment of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.ORCID https://orcid.org/0000-0002-0651-2213
Hye-Sun ParkDepartment of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3275-1437
Sang-Min ParkDepartment of Orthopaedic Surgery, Seoul National University College of Medicine and Seoul National University Bundang Hospital, Seongnam, Korea. psmini@naver.com.ORCID https://orcid.org/0000-0001-6171-3256
Young-Kyun LeeDepartment of Orthopaedic Surgery, Seoul National University College of Medicine and Seoul National University Bundang Hospital, Seongnam, Korea. ykleemd@gmail.com.ORCID https://orcid.org/0000-0001-6564-4294
Tae-Young KimDepartment of Orthopaedic Surgery, School of Medicine, Konkuk University, Seoul, Korea.ORCID https://orcid.org/0000-0003-2624-7629
Yong-Chan HaDepartment of Orthopaedic Surgery, College of Medicine, Chung-Ang University, Seoul, Korea.ORCID https://orcid.org/0000-0002-6249-0581
Yumie RheeDepartment of Internal Medicine, Endocrine Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4227-5638
Kyung-Hoi KooDepartment of Orthopaedic Surgery, Seoul National University Bundang Hospital and Kay Joint Center at Cheil Orthopaedic Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-5251-2911
Yonsei University · KRSeoul National University Bundang Hospital · KRChung-Ang University · KRKonkuk University · KRUlsan College · KR

Funding

Korea Health Industry Development Institute HI18C0284
6 · The paper itself

Abstract

backgroundWe analyzed the International Classification of Diseases, 10th edition (ICD-10) diagnostic codes, procedure codes, and radiographic image codes for vertebral fracture (VF) used in the database of Health Insurance Review and Assessment Service (HIRA) of Korea to establish a validated operational definition for identifying patients with osteoporotic VF in claims data.

methodsWe developed three operational definitions for detecting VFs using 9 diagnostic codes, 5 procedure codes and 4 imaging codes. Medical records and radiographs of 2,819 patients, who had primary and subordinated codes of VF between January 2016 and December 2016 at two institutions, were reviewed to detect true vertebral fractures. We evaluated the sensitivity and positive predictive value (PPV) of the operational definition in detecting true osteoporotic VF and obtained the receiver operating characteristic (ROC) curve.

resultsAmong the 2,819 patients who had primary or secondary diagnosis codes for VF, 995 patients satisfied at least one of the criteria for the operational definition of osteoporotic VF. Of these patients, 594 were judged as having true fractures based on medical records and radiographic examinations. The sensitivity and PPV were 62.5 (95% confidence interval [CI], 59.4-65.6) and 59.7(95% CI, 56.6-62.8) respectively. In the receiver operating characteristic analysis, area under the curve (AUC) was 0.706 (95% CI, 0.688-0.724).

conclusionOur findings demonstrate the validity of our operational definitions to identify VFs more accurately using claims data. This algorithm to identify VF is likely to be useful in future studies for diagnosing osteoporotic VF.

Indexed as

Osteoporotic FracturesSpinal FracturesAlgorithmsDatabases, FactualHumansRadiographyClaim DatabaseOperational DefinitionOsteoporosisVertebral Fracture

Identifiers

PMID35971763
PMCPMC9424695
OpenAlexW4289732925

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.