Evidence map›Paper›PMID 35971617›Full record

ArticleFEBS letters2022

cAMP-induced decrease in cell-surface laminin receptor and cellular prion protein attenuates amyloid-β uptake and amyloid-β-induced neuronal cell death.

Rayudu Gopalakrishna, Charlotte Y Lin, Andrew Oh, Calvin Le, Seolyn Yang, Alexandra Hicks, Mark S Kindy, William J Mack, Narayan R Bhat

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rayudu GopalakrishnaDepartment of Integrative Anatomical Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-0398-3116
Charlotte Y LinDepartment of Integrative Anatomical Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Andrew OhDepartment of Integrative Anatomical Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Calvin LeDepartment of Integrative Anatomical Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Seolyn YangDepartment of Integrative Anatomical Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Alexandra HicksDepartment of Integrative Anatomical Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Mark S KindyDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA.
William J MackDepartment of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Narayan R BhatDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC, USA.
University of Southern California · USMedical University of South Carolina · USUniversity of South Florida · US

Funding

Translational potential of the internalization of Nogo-A receptor to enhance axonal regeneration after strokeR21NS116720 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GOPALAKRISHNA, RAYUDU, MACK, WILLIAM J · 2020 to 2020
$454k
Redox-based Targeting of Cerebrovascular Dysfunction in ADR21AG059422 · NIA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BHAT, NARAYAN R · 2018 to 2019
$411k
BLRD Research Career Scientist Award ApplicationIK6BX005239 · VA · JAMES A. HALEY VA MEDICAL CENTER · PI KINDY, MARK S. · 2020 to 2025
–
BLRD VA IK6 BX005239NIA NIH HHS R21 AG059422NINDS NIH HHS R21 NS116720
6 · The paper itself

Abstract

Previous studies have shown that amyloid-β oligomers (AβO) bind with high affinity to cellular prion protein (PrP

Indexed as

Amyloid beta-PeptidesPrPC ProteinsCell DeathLamininPituitary Adenylate Cyclase-Activating PolypeptidePrion ProteinsReceptors, LamininAmyloid beta-PeptidesLamininPituitary Adenylate Cyclase-Activating PolypeptidePrion ProteinsPrPC ProteinsReceptors, Laminin67 kDa laminin receptoramyloid-βcAMPcellular prion proteinPACAPprotein kinase A

Identifiers

PMID35971617
PMCPMC9712173
OpenAlexW4290018560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.