Evidence map›Paper›PMID 35971346›Full record

ArticleCureus2022

Clinical Characteristics and Outcomes of COVID-19 Acute Respiratory Distress Syndrome (ARDS) Survivors in Early Pandemic: A Single Healthcare System Retrospective Study.

Cyrus A Vahdatpour, Sheila De Young, Johnny F Jaber, Joy Ayyoub, Thomas Sommers, Christopher Wen, Tristan Lim, Olutosin Owoyemi, Kathleen Davin, Paul Kinniry and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Cyrus A VahdatpourPulmonary and Critical Care Medicine, University of Florida, Gainesville, USA.
Sheila De YoungMedicine, Pennsylvania Hospital, Philadelphia, USA.
Johnny F JaberPulmonary and Critical Care Medicine, University of Florida College of Medicine, Gainesville, USA.
Joy AyyoubPulmonary and Critical Care Medicine, Temple University Hospital, Philadelphia, USA.
Thomas SommersMedical Education, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Christopher WenMedical Education, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Tristan LimMedical Education, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Olutosin OwoyemiMedical Education, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Kathleen DavinMedical Education, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Paul KinniryPulmonary and Critical Care Medicine, Pennsylvania Hospital, Philadelphia, USA.
Onyeka NwankwoInfectious Diseases, Pennsylvania Hospital, Philadelphia, USA.
Adam AustinPulmonary and Critical Care Medicine, University of Florida, Gainesville, USA.
Pennsylvania Hospital · USFlorida College · USPulmonary and Critical Care Associates · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute respiratory distress syndrome (ARDS) management in the intensive care unit (ICU) has attracted strong interest since the start of the COVID-19 pandemic. Our retrospective study aims to describe the outcomes and predictors of mortality of ARDS associated with COVID-19 within one university-based healthcare system.

methodsWe identified 165 patients within our healthcare system during the months of April 2020 through July 2020, who were admitted to our medical ICUs and eligible for our study. Baseline patient characteristics, ICU and hospital course information, ICU interventions, ventilator settings, and hospital complications were collected and analyzed using descriptive statistical techniques.

resultsOur cohort had an average age of 64. No significant difference in mortality was identified with male vs. female gender or BMI. Most of the patient cohort was identified as black (68.2%). The overall mortality of our cohort was 38.2%. Hyperlipidemia, coronary artery disease, and chronic obstructive pulmonary disease were all associated with higher mortality. There was a significant difference in mortality between those with higher observed ventilator plateau pressures at 24 hours and higher driving pressures at 24 hours.

conclusionCOVID-19-associated ARDS is associated with significant mortality. Physicians should be aware of pre-existing conditions potentially related to worse outcomes so that they receive an appropriate level of care in a timely manner. Ventilator management should focus on maintaining low intra-thoracic pressure changes. Prospective studies are needed to guide COVID-19-associated ARDS management.

Indexed as

acute respiratory distress syndrome [ards]covid 19covid-19 respiratory failurecritical care outcomesinvasive mechanical ventilation

Identifiers

PMID35971346
PMCPMC9372924
OpenAlexW4285085867

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.