Evidence map›Paper›PMID 35971278›Full record

SynthesisReviews in medical virology2022

Effect of corticosteroid therapy on mortality in COVID-19 patients-A systematic review and meta-analysis.

Chirag Patel, Krupanshu Parmar, Dipanshi Patel, Sandip Patel, Devang Sheth, Jayesh V Beladiya

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Reviews in medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. IL-6 Blockade in Cytokine Storm Syndromes.Advances in experimental medicine and biology · 2024
    Review
  8. Article
  9. Article
  10. Severe COVID-19: Drugs and Clinical Trials.Journal of clinical medicine · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Post-COVID-19 incidentally discovered adrenal findings (a CT-focused real-life study).Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chirag PatelDepartment of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.
Krupanshu ParmarDepartment of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.
Dipanshi PatelDepartment of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.
Sandip PatelDepartment of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.
Devang ShethDepartment of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.
Jayesh V BeladiyaDepartment of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India.ORCID 0000-0001-7203-7855
B.J. Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of corticosteroid therapy is still controversial on prevention of mortality in coronavirus disease-2019 (COVID-19). The objective of this study is to investigate the effect of corticosteroids on mortality. This systematic review was performed as per preferred reporting items for systematic reviews and meta-analyses guidelines. A systematic search was performed at different databases namely Medline/PubMed, Cochrane and Google scholar on 10 February 2022. A pooled estimate for effect of corticosteroid therapy on mortality was calculated as outcome of study. Risk bias analysis and Newcastle Ottawa Scale were used to assess the quality of randomized control trial (RCT) and cohort studies, respectively. Cochran's Q test and the I

Indexed as

COVID-19 Drug TreatmentAdrenal Cortex HormonesCohort StudiesHumansAdrenal Cortex HormonescorticosteroidsCOVID-19deathdexamethasonefatalitymethylprednisolonemortalitySARS-CoV-2

Identifiers

PMID35971278
PMCPMC9538928
OpenAlexW4291915033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.