ReviewBMC oral health2022
Generalized pulp canal obliteration in a patient on long-term glucocorticoids: a case report and literature review.
Review in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Pulp calcification and pulp canal obliteration: from biological mechanisms to contemporary clinical management and digital navigation.The Saudi dental journal · 2026Review
- Static Guided Endodontics in Primary Endodontic Treatment of Anterior Teeth: A Narrative Review.Dentistry journal · 2026Review
- Guided Endodontic Treatment of an Upper Lateral Incisor: A Successful Outcome in the Presence of Procedural Errors-A Case Report.Case reports in dentistry · 2025Article
- Guided Endodontic Treatment of Mandibular Incisor with Pulp Canal Obliteration following Dental Trauma: A Case Report.Iranian endodontic journal · 2024Article
- Assessment of the Correlation Between Systemic Conditions and Pulp Canal Calcification: A Case-Control Study.Cureus · 2023Article
- Management of paroxysmal nocturnal hemoglobinuria (PNH).Journal of clinical laboratory analysis · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe calcification of the tooth pulp is a pathological condition that occurs in response to various factors. A uncommon haematological condition known as paroxysmal nocturnal haemoglobinuria (PNH) is characterized by bouts of haemolysis, and it requires long-term use of glucocorticoids (GCs). CASE PRESENTATION: A female patient who was diagnosed with PNH and had a history of long-term use of GCs came to our department for root canal therapy (RCT) for teeth 25, 26, and 27. The radiographs showed generalized pulp canal obliteration (PCO) in most of the patients. None of these teeth (25, 26, or 27) were sensitive to percussion, and they did not respond to thermal or electrical sensitivity tests. A diagnose of pulp necrosis was made for these teeth. RCT was carried out with the help of an oral microscope, and then a prosthodontic procedure was created for the teeth.
conclusionsBased on the patient's long history use of GCs and a series of related studies, we conclude that the long-term usage of GCs contributes significantly to the onset of PCO.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.