Evidence map›Paper›PMID 35970935›Full record

ReviewPediatric research2023

SARS-CoV-2 infection in children and implications for vaccination.

Jordan Nathanielsz, Zheng Quan Toh, Lien Anh Ha Do, Kim Mulholland, Paul V Licciardi

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
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  12. Hybrid response to SARS-CoV-2 andHuman vaccines & immunotherapeutics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jordan NathanielszSchool of Medicine, Deakin University, Geelong, VIC, Australia.
Zheng Quan TohInfection and Immunity, Murdoch Children's Research Institute, Melbourne, VIC, Australia.
Lien Anh Ha DoInfection and Immunity, Murdoch Children's Research Institute, Melbourne, VIC, Australia.
Kim MulhollandInfection and Immunity, Murdoch Children's Research Institute, Melbourne, VIC, Australia.
Paul V LicciardiInfection and Immunity, Murdoch Children's Research Institute, Melbourne, VIC, Australia. paul.licciardi@mcri.edu.au.
Murdoch Children's Research Institute · AUAlfred Health · AULondon School of Hygiene & Tropical Medicine · GBUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic caused by novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for more than 500 million cases worldwide as of April 2022. Initial estimates in 2020 found that children were less likely to become infected with SARS-CoV-2 and more likely to be asymptomatic or display mild COVID-19 symptoms. Our early understanding of COVID-19 transmission and disease in children led to a range of public health measures including school closures that have indirectly impacted child health and wellbeing. The emergence of variants of concern (particularly Delta and Omicron) has raised new issues about transmissibility in children, as preliminary data suggest that children may be at increased risk of infection, especially if unvaccinated. Global national prevalence data show that SARS-CoV-2 infection in children and adolescents is rising due to COVID-19 vaccination among adults and increased circulation of Delta and Omicron variants. To mitigate this, childhood immunisation programmes are being implemented globally to prevent direct and indirect consequences of COVID-19 including severe complications (e.g., MIS-C), debilitating long-COVID symptoms, and the indirect impacts of prolonged community and school closures on childhood education, social and behavioural development and mental health. This review explores the current state of knowledge on COVID-19 in children including COVID-19 vaccination strategies. IMPACT: Provides an up-to-date account of SARS-CoV-2 infections in children. Discusses the direct and indirect effects of COVID-19 in children. Provides the latest information on the current state of global COVID-19 vaccination in children.

Indexed as

COVID-19AdolescentAdultChildCOVID-19 VaccinesHumansPandemicsPost-Acute COVID-19 SyndromeSARS-CoV-2Systemic Inflammatory Response SyndromeVaccinationCOVID-19 Vaccines

Identifiers

PMID35970935
PMCPMC9376896
OpenAlexW4291535748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.