ArticleNature biomedical engineering2023
A low-power stretchable neuromorphic nerve with proprioceptive feedback.
Article in Nature biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 169 citations in OpenAlex.
- Advances in Stretchable Polymer Semiconductors: Design Strategies and Applications in Human-Machine Interaction and Bioelectronics.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Multiscale Manufacturing of Organic Electronic Materials.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Gate Metal-Driven Sensing and Memory Bifunctionality in Intrinsically Stretchable Organic Electrochemical Transistors for Soft Neuromorphic Systems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- From sound sensing to neural control.Nature materials · 2026Article
- An iontronic reservoir for highly robust neuromorphic prosthesis.Nature materials · 2026Article
- Ion-shielding ultrathin encapsulation with hot-press bonded interface enables chronic stretchable bioelectronics.Science advances · 2026Article
- Neuromorphic Technologies for Neuroengineering: From Adaptive Stimulation to SNN-Based Inference and Deployable Biointerfaces.Sensors (Basel, Switzerland) · 2026Review
- The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Organic Transistor-Based Neuromorphic Electronics and Their Recent Applications.Small methods · 2026Review
- Intrinsically stretchable all-polymer neuromorphic visual adaptive transistors based on multidimensional-phase-separation-induced micromesh.Nature communications · 2026Article
- Organic Electrochemical Transistors for Neuromorphic Devices and Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Multiscale Engineering of Ion-Conducting Gels for Sustainable Bioelectronic Systems.Small methods · 2026Review
- A Bioinspired Perceptual Sensor for Spatiotemporal Decoding of Haptic and Pain Stimuli in Prostheses.Cyborg and bionic systems (Washington, D.C.) · 2026Article
- Highly reconfigurable neuronlike conductive networks through nanophase structure engineering.Nature communications · 2025Article
- Diffusion-Plating AlMicromachines · 2025Article
- Role of Amorphous Phases in Mixed Conduction of Conjugated Regioblock Copolymers for Organic Electrochemical Synaptic Transistors.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Toward Natural Limb Function: A New Era in Prosthetic Innovation.Annals of neurology · 2025Review
- Artificial Nervous Systems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- A wireless optogenetic stimulation system for long-term function evaluation of mice forelimb with sub-nerve resolution.Nature communications · 2025Article
- Hybrid 3D printing of bio-inspired artificial slowly adapting type II afferents.Nature communications · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 3 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
By relaying neural signals from the motor cortex to muscles, devices for neurorehabilitation can enhance the movement of limbs in which nerves have been damaged as a consequence of injuries affecting the spinal cord or the lower motor neurons. However, conventional neuroprosthetic devices are rigid and power-hungry. Here we report a stretchable neuromorphic implant that restores coordinated and smooth motions in the legs of mice with neurological motor disorders, enabling the animals to kick a ball, walk or run. The neuromorphic implant acts as an artificial efferent nerve by generating electrophysiological signals from excitatory post-synaptic signals and by providing proprioceptive feedback. The device operates at low power (~1/150 that of a typical microprocessor system), and consists of hydrogel electrodes connected to a stretchable transistor incorporating an organic semiconducting nanowire (acting as an artificial synapse), connected via an ion gel to an artificial proprioceptor incorporating a carbon nanotube strain sensor (acting as an artificial muscle spindle). Stretchable electronics with proprioceptive feedback may inspire the further development of advanced neuromorphic devices for neurorehabilitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.