Evidence map›Paper›PMID 35970471›Full record

ArticleNeuroImage2022

Cross-Axis Dynamic Field Compensation of Optically Pumped Magnetometer Arrays for MEG.

Stephen E Robinson, Amaia Benitez Andonegui, Tom Holroyd, K Jeramy Hughes, Orang Alem, Svenja Knappe, Tyler Maydew, Andreas Griesshammer, Allison Nugent

Open access · goldAbstract read
In one paragraph

Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 48 citations in OpenAlex.

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  4. Combining video telemetry and wearable MEG for naturalistic imaging.Imaging neuroscience (Cambridge, Mass.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Stephen E RobinsonMEG Core Facility, NIMH/NIH, Bethesda, MD. Electronic address: robinsonse@mail.nih.gov.
Amaia Benitez AndoneguiMEG Core Facility, NIMH/NIH, Bethesda, MD.
Tom HolroydMEG Core Facility, NIMH/NIH, Bethesda, MD.
K Jeramy HughesFieldLine Inc., Boulder, CO; University of Colorado Boulder, Boulder, CO.
Orang AlemFieldLine Inc., Boulder, CO; University of Colorado Boulder, Boulder, CO.
Svenja KnappeFieldLine Inc., Boulder, CO; University of Colorado Boulder, Boulder, CO.
Tyler MaydewFieldLine Inc., Boulder, CO.
Andreas GriesshammerFieldLine Inc., Boulder, CO.
Allison NugentMEG Core Facility, NIMH/NIH, Bethesda, MD.
National Institutes of Health · USUniversity of Colorado Boulder · US

Funding

NIMH MEG Core FacilityZICMH002889 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI NUGENT, ALLISON · 2009 to 2025
$31.4M
BRAIN project (Nugent)ZIAMH002975 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI NUGENT, ALLISON · 2020 to 2021
$518k
Intramural NIH HHS ZIA MH002975Intramural NIH HHS ZIC MH002889
6 · The paper itself

Abstract

We present dynamic field compensation (DFC), whereby three-axis field measurements from reference magnetometers are used to dynamically maintain null at the alkali vapor cells of an array of primary sensors that are proximal to a subject's scalp. Precision measurement of the magnetoencephalogram (MEG) by zero-field optically pumped magnetometer (OPM) sensors requires that sensor response is linear and sensor gain is constant over time. OPMs can be operated in open-loop mode, where the measured field is proportional to the output at the demodulated photodiode output, or in closed-loop, where on-board coils are dynamically driven to maintain the internal cell at zero field in the measurement direction. While OPMs can be operated in closed-loop mode along all three axes, this can increase sensor noise and poses engineering challenges. Uncompensated fluctuations in the ambient field along any statically nulled axes perturb the measured field by tipping the measurement axis and altering effective sensor gain - a phenomenon recently referred to as cross-axis projection error (CAPE). These errors are particularly problematic when OPMs are allowed to move in the remnant background field. Sensor gain-errors, if not mitigated, preclude precision measurements with OPMs operating in the presence of ambient field fluctuations within a typical MEG laboratory. In this manuscript, we present the cross-axis dynamic field compensation (DFC) method for maintaining zero field dynamically on all three axes of each sensor in an array of OPMs. Together, DFC and closed-loop operation strongly attenuate errors introduced by CAPE. This method was implemented by using three orthogonal reference sensors together with OPM electronics that permit driving each sensor's transverse field coils dynamically to maintain null field across its OPM measurement cell. These reference sensors can also be used for synthesizing 1

Indexed as

BrainMagnetoencephalographyHumansMagnetic FieldsScalpCross-axis projection errorDynamic field compensationLinearityMagnetoencephalographyOptically pumped magnetometerSynthetic gradiometer

Identifiers

PMID35970471
PMCPMC9464713
OpenAlexW4291111393

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.