Evidence map›Paper›PMID 35970373›Full record

ReviewInternational journal of radiation oncology, biology, physics2023

A Primer on Radiopharmaceutical Therapy.

Kilian E Salerno, Soumyajit Roy, Cathy Ribaudo, Teresa Fisher, Ravi B Patel, Esther Mena, Freddy E Escorcia

Abstract readReview
In one paragraph

Review in International journal of radiation oncology, biology, physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Development of novel GPC2-directed radiotheranostics and CAR T cell therapy for neuroblastoma.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  2. Article
  3. Comparative theranostic efficacy ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Enhanced radiotheranostic targeting of integrinActa pharmaceutica Sinica. B · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. The development ofEJNMMI radiopharmacy and chemistry · 2024
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. The Future of Radioactive Medicine.Radiation research · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kilian E SalernoRadiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Soumyajit RoyRadiation Oncology Department, Rush Medical Center, Chicago, Illinois.
Cathy RibaudoDivision of Radiation Safety, National Institutes of Health, Bethesda, Maryland.
Teresa FisherDivision of Radiation Safety, National Institutes of Health, Bethesda, Maryland.
Ravi B PatelRadiation Oncology Department, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Esther MenaMolecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Freddy E EscorciaRadiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Electronic address: freddy.escorcia@nih.gov.

Funding

Development of new antibody-based cancer therapiesZIABC010891 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HO, MITCHELL · 2009 to 2025
$21.4M
Engineering HCC-selective PET agentZIABC011800 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ESCORCIA, FREDDY · 2018 to 2025
$10.6M
VLA-4–targeted 67Cu-LLP2A preconditioning enhances efficacy of T-cell-based adoptive immunotherapyR01CA275766 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ravi Bhasker Patel · 2023 to 2026
$2.4M
Utilization of molecular targeted radionuclides to prime immune responses at local and distant metastatic tumor sitesK08CA241319 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI PATEL, RAVI BHASKER · 2019 to 2023
$629k
Antibody Therapy of CancerZ01BC010891 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HO, MITCHELL · 2008 to 2008
$56k
Intramural NIH HHS Z01 BC010891Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA BC010891Intramural NIH HHS ZIA BC011800NCI NIH HHS K08 CA241319NCI NIH HHS R01 CA275766
6 · The paper itself

Abstract

The goal of this article is to serve as a primer for the United States-based radiation oncologist who may be interested in learning more about radiopharmaceutical therapy (RPT). Specifically, we define RPT, review the data behind its current and anticipated indications, and discuss important regulatory considerations for incorporating it into clinical practice. RPT represents an opportunity for radiation oncologists to leverage 2 key areas of expertise, namely therapeutic radiation therapy and oncology, and apply them in a distinct context in collaboration with nuclear medicine and medical oncology colleagues. Although not every radiation oncologist will incorporate RPT into their day-to-day practice, it is important to understand the role for this modality and how it can be appropriately used in select patients.

Indexed as

Medical OncologyRadiopharmaceuticalsHumansRadiation OncologistsRadionuclide ImagingUnited StatesRadiopharmaceuticals

Identifiers

PMID35970373
PMCPMC9772089

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.