Evidence map›Paper›PMID 35969814›Full record

ReviewJournal of natural products2022

Antiviral Profiling of C-18- or C-19-Functionalized Semisynthetic Abietane Diterpenoids.

Miguel A González-Cardenete, Damir Hamulić, Francisco J Miquel-Leal, Natalia González-Zapata, Orlando J Jimenez-Jarava, Yaneth M Brand, Laura C Restrepo-Mendez, Marlen Martinez-Gutierrez, Liliana A Betancur-Galvis, Maria L Marín

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of natural products, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Miguel A González-CardeneteInstituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de Valencia-Consejo Superior de Investigaciones Científicas, Avda de los Naranjos s/n, 46022 Valencia, Spain.
Damir HamulićInstituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de Valencia-Consejo Superior de Investigaciones Científicas, Avda de los Naranjos s/n, 46022 Valencia, Spain.
Francisco J Miquel-LealInstituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de Valencia-Consejo Superior de Investigaciones Científicas, Avda de los Naranjos s/n, 46022 Valencia, Spain.
Natalia González-ZapataInstituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de Valencia-Consejo Superior de Investigaciones Científicas, Avda de los Naranjos s/n, 46022 Valencia, Spain.
Orlando J Jimenez-JaravaGrupo de Investigaciones Dermatológicas, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia, 050010 Medellín, Colombia.
Yaneth M BrandGrupo de Investigaciones Dermatológicas, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia, 050010 Medellín, Colombia.
Laura C Restrepo-MendezGrupo de Investigación en Ciencias Animales-GRICA, Universidad Cooperativa de Colombia, 680001 Bucaramanga, Colombia.
Marlen Martinez-GutierrezGrupo de Investigación en Ciencias Animales-GRICA, Universidad Cooperativa de Colombia, 680001 Bucaramanga, Colombia.
Liliana A Betancur-GalvisGrupo de Investigaciones Dermatológicas, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia, 050010 Medellín, Colombia.
Maria L MarínInstituto de Tecnología Química (UPV-CSIC), Universitat Politècnica de Valencia-Consejo Superior de Investigaciones Científicas, Avda de los Naranjos s/n, 46022 Valencia, Spain.
Universidad de Antioquia · COUniversitat Politècnica de València · ESUniversidad Cooperativa de Colombia · COConsejo Superior de Investigaciones Científicas · ESInstituto de Tecnología Química · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral infections affect several million patients annually. Although hundreds of viruses are known to be pathogenic, only a few can be treated in the clinic with available antiviral drugs. Naturally based pharmacotherapy may be a proper alternative for treating viral diseases. Several natural and semisynthetic abietane-type diterpenoids have shown important antiviral activities. In this study, a biological evaluation of a number of either C-18- or C-19-functionalized known semisynthetic abietanes against

Indexed as

Chikungunya virusVirusesZika VirusZika Virus InfectionAbietanesAntiviral AgentsHumansVirus ReplicationAbietanesAntiviral Agents

Identifiers

PMID35969814
PMCPMC9425435
OpenAlexW4291910000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.