Evidence map›Paper›PMID 35969785›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Intestinal tissue-resident T cell activation depends on metabolite availability.

Špela Konjar, Cristina Ferreira, Filipa Sofia Carvalho, Patrícia Figueiredo-Campos, Júlia Fanczal, Sofia Ribeiro, Vanessa Alexandra Morais, Marc Veldhoen

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  4. Review
  5. Article
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  8. Article
  9. Targeting tumor metabolism to augment CD8Journal of pharmaceutical analysis · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. DEFA5-producing CD4Frontiers in immunology · 2025
    Article
  14. Review
  15. Article
  16. Optimizing CD8Experimental hematology & oncology · 2024
    Review
  17. A Paradoxical Tumor Antigen Specific Response in the Liver.bioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Review
  20. Prostaglandin ENature communications · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Špela KonjarInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa 1649-028, Portugal.
Cristina FerreiraInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa 1649-028, Portugal.ORCID 0000-0001-6746-932X
Filipa Sofia CarvalhoInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa 1649-028, Portugal.ORCID 0000-0002-0074-0741
Patrícia Figueiredo-CamposInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa 1649-028, Portugal.ORCID 0000-0002-9808-6230
Júlia FanczalInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa 1649-028, Portugal.ORCID 0000-0001-7356-3857
Sofia RibeiroInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa 1649-028, Portugal.ORCID 0000-0002-0265-0416
Vanessa Alexandra MoraisInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa 1649-028, Portugal.ORCID 0000-0002-0830-0548
Marc VeldhoenInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa 1649-028, Portugal.ORCID 0000-0002-1478-9562
University of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The metabolic capacity of many cells is tightly regulated and can adapt to changes in metabolic resources according to environmental changes. Tissue-resident memory (T

Indexed as

CD8-Positive T-LymphocytesIntraepithelial LymphocytesMemory T CellsIntestinal MucosaIntestinesLymphocyte ActivationOxidative PhosphorylationglucoseIELsmetabolismT cellstissue-resident memory T cells

Identifiers

PMID35969785
PMCPMC9411733
OpenAlexW4291804708

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.