Evidence map›Paper›PMID 35969758›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Comparative genomics uncovers the evolutionary history, demography, and molecular adaptations of South American canids.

Daniel E Chavez, Ilan Gronau, Taylor Hains, Rebecca B Dikow, Paul B Frandsen, Henrique V Figueiró, Fabrício S Garcez, Ligia Tchaicka, Rogério C de Paula, Flávio H G Rodrigues and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
24.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  9. Digestive anatomy and diet of free-ranging maned wolf (Mammalian biology = Zeitschrift fur Saugetierkunde · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Pathogens (Basel, Switzerland) · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. ElucidatingFrontiers in parasitology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 12 institutions in 2 countries.

Daniel E ChavezDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095.
Ilan GronauEfi Arazi School of Computer Science, Reichman University, Herzliya 46150, Israel.
Taylor HainsCommittee on Evolutionary Biology, University of Chicago, Chicago, IL 60637.
Rebecca B DikowData Science Lab, Office of the Chief Information Officer, Smithsonian Institution, Washington, DC 20560.
Paul B FrandsenData Science Lab, Office of the Chief Information Officer, Smithsonian Institution, Washington, DC 20560.ORCID 0000-0002-4801-7579
Henrique V FigueiróSmithsonian's National Zoo and Conservation Biology Institute, Center for Species Survival, Front Royal, VA 22630.ORCID 0000-0002-8368-7156
Fabrício S GarcezSchool of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, 90619-900, Brazil.
Ligia TchaickaRede de Biodiversidade e Biotecnologia da Amazônia, Curso de Pós-Graduação em Recursos Aquáticos e Pesca, Universidade Estadual do Maranhão, São Luis, 2016-8100, Brazil.ORCID 0000-0003-1993-1377
Rogério C de PaulaCentro Nacional de Pesquisa e Conservação de Mamíferos Carnívoros, Instituto Chico Mendes de Conservação da Biodiversidade, 12952-011, Atibaia, Brazil.ORCID 0000-0003-1943-8320
Flávio H G RodriguesDepartment of Genetics, Ecology and Evolution, Universidade Federal de Minas Gerais, Belo Horizonte, 31270-901, Brazil.
Rodrigo S P JorgeCentro Nacional de Avaliação da Biodiversidade e de Pesquisa e Conservação do Cerrado, Instituto Chico Mendes de Conservação da Biodiversidade, Brasilia, 70670-350, Brazil.
Edson S LimaPrivate address, Nova Xavantina, MT, 78690-000, Brazil.
Nucharin SongsasenSmithsonian's National Zoo and Conservation Biology Institute, Center for Species Survival, Front Royal, VA 22630.
Warren E JohnsonSmithsonian's National Zoo and Conservation Biology Institute, Center for Species Survival, Front Royal, VA 22630.
Eduardo EizirikSchool of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, 90619-900, Brazil.ORCID 0000-0002-9658-0999
Klaus-Peter KoepfliSmithsonian's National Zoo and Conservation Biology Institute, Center for Species Survival, Front Royal, VA 22630.
Robert K WayneDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095.
Smithsonian Conservation Biology Institute · USInstituto Chico Mendes de Conservação da Biodiversidade · BRUniversity of California, Los Angeles · USBrigham Young University · USGeorge Mason University · USInstituto Pró-Carnívoros · BRPontifícia Universidade Católica do Rio Grande do Sul · BRSmithsonian Institution · USThe University of Texas at Austin · USUniversidade Estadual do Maranhão · BRUniversidade Federal de Minas Gerais · BRUniversity of Chicago · US

Funding

Genetic Mechanisms and Evolution-RenewalT32GM139782 · NIGMS · UNIVERSITY OF CHICAGO · PI Francesca Luca, John Novembre · 2021 to 2026
$5.1M
NIGMS NIH HHS T32 GM139782
6 · The paper itself

Abstract

The remarkable radiation of South American (SA) canids produced 10 extant species distributed across diverse habitats, including disparate forms such as the short-legged, hypercarnivorous bush dog and the long-legged, largely frugivorous maned wolf. Despite considerable research spanning nearly two centuries, many aspects of their evolutionary history remain unknown. Here, we analyzed 31 whole genomes encompassing all extant SA canid species to assess phylogenetic relationships, interspecific hybridization, historical demography, current genetic diversity, and the molecular bases of adaptations in the bush dog and maned wolf. We found that SA canids originated from a single ancestor that colonized South America 3.9 to 3.5 Mya, followed by diversification east of the Andes and then a single colonization event and radiation of

Indexed as

Adaptation, PhysiologicalCanidaePhylogenyAnimalsDemographyGenetic VariationGenomicsSouth AmericaCanidaegenomesneotropicspositive selectionSouth America

Identifiers

PMID35969758
PMCPMC9407222
OpenAlexW4291652208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.