ReviewJournal of animal science and technology2022
Selection of appropriate biomatrices for studies of chronic stress in animals: a review.
Review in Journal of animal science and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Effects of surgical timing on inflammatory responses, oxidative stress, and immune modulation in Wagyu calves following castration.BMC veterinary research · 2026Article
- Beyond the Mission: Long-Term Endocrine Dynamics in Search and Rescue Dog-Handler Teams.Animals : an open access journal from MDPI · 2026Article
- Beyond cortisol: evaluating serotonin, brain-derived neurotrophic factor, and oxytocin as indicators of equine welfare across three training regimens.BMC veterinary research · 2026Article
- Preliminary Investigation on Salivary Enzymes of Massese Sheep.Animals : an open access journal from MDPI · 2026Article
- Optimizing tryptophan supplementation for stress reduction and enhanced productivity in aging laying hens.Journal of animal science and technology · 2026Article
- When touch is stressful: acute endocrine and behavioral responses of domestic rabbits to unfamiliar human handling.Frontiers in veterinary science · 2026Article
- Evaluation of earwax and hair cortisol concentration in relation to environmental stressors in Hanwoo cattle.Veterinary research communications · 2025Article
- Genome-wide association and fine-mapping analyses identify novel candidate genes affecting serum cortisol levels using imputed whole-genome sequencing data in pigs.Journal of animal science and technology · 2025Article
- Seasonal indices of nutrition and stress in a northern population of snowshoe hares.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025Article
- RETRACTED: Hair Cortisol and Fe-BARQ: Evaluating Chronic Stress and Behavior in Cats with Chronic Kidney Disease.Animals : an open access journal from MDPI · 2025Article
- Stress level in companion dogs with and without atopic dermatitis.Journal of animal science and technology · 2025Article
- Impact of environmental enrichment on growth, behavior, and welfare of weanling piglets from pre-weaning to 6 weeks of age.Journal of animal science and technology · 2025Article
- Effect of a Broiler-Specific Light Spectrum on Growth Performance and Adrenocortical Activity in Chickens: A Pilot Study on a Commercial Farm.Veterinary sciences · 2024Article
- Assessment of Heat Processing Effects on Cortisol Concentration in Dairy Milk Products.Food science of animal resources · 2024Article
- Effect of organic solvents on earwax cortisol extraction in Hanwoo cattle.Journal of animal science and technology · 2024Article
- Article
- Milk microbiota of Holstein Friesian cattle reared in Lahore: Association with mastitis.Saudi journal of biological sciences · 2024Article
- Fish Responses to Alternative Feeding Ingredients under Abiotic Chronic Stress.Animals : an open access journal from MDPI · 2024Review
- Hair cortisol of pigs in mixed organic farms: the influence of season, breeding system and sex.Frontiers in veterinary science · 2024Article
- Protective Effects ofFood science of animal resources · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cortisol and corticosterone, hormones traditionally considered biomarkers of stress, can be measured in fluid biomatrices (e.g., blood, saliva) from live animals to evaluate conditions at sampling time, or in solid biomatrices (e.g., hair, feather) from live or dead animals to obtain information regarding long-term changes. Using these biomarkers to evaluate physiological stress responses in domestic animals may be challenging due to the diverse characteristics of biomatrices for potential measurement. Ideally, a single measurement from the biomatrix should be sufficient for evaluating chronic stress. The availability of appropriate and cost-effective immunoassay methods for detecting the biomarkers should also be considered. This review discusses the strengths and limitations of different biomatrices with regard to ensuring the highest possible reliability for chronic stress evaluation. Overall, solid biomatrices require less frequent sampling than other biomatrices, resulting in greater time- and cost-effectiveness, greater ease of use, and fewer errors. The multiplex immunoassay can be used to analyze interactions and correlations between cortisol and other stress biomarkers in the same biomatrix. In light of the lack of information regarding appropriate biomatrices for measuring chronic stress, this review may help investigators set experimental conditions or design biological research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.