Evidence map›Paper›PMID 35969692›Full record

ArticleJournal of the American Chemical Society2022

An Enantioselective Suzuki-Miyaura Coupling To Form Axially Chiral Biphenols.

Robert Pearce-Higgins, Larissa N Hogenhout, Philip J Docherty, David M Whalley, Padon Chuentragool, Najung Lee, Nelson Y S Lam, Thomas M McGuire, Damien Valette, Robert J Phipps

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  4. Spin-Correlated Luminescence of Mechanically Generated Radical Species.Angewandte Chemie (International ed. in English) · 2026
    Article
  5. Article
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  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
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  14. Article
  15. Intermolecular Asymmetric Arylative Dearomatization of 1-Naphthols.Journal of the American Chemical Society · 2024
    Article
  16. Article
  17. Atroposelective catalysis.Nature reviews. Chemistry · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Robert Pearce-HigginsYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.
Larissa N HogenhoutYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.
Philip J DochertyYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.
David M WhalleyYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.
Padon ChuentragoolYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.ORCID 0000-0002-7466-8455
Najung LeeYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.
Nelson Y S LamYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.ORCID 0000-0002-9307-0619
Thomas M McGuireOncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom.
Damien ValetteGlaxoSmithKline Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, United Kingdom.ORCID 0000-0002-1620-3502
Robert J PhippsYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.ORCID 0000-0002-7383-5469

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Axial chirality features prominently in molecules of biological interest as well as chiral catalyst designs, and atropisomeric 2,2'-biphenols are particularly prevalent. Atroposelective metal-catalyzed cross-coupling is an attractive and modular approach to access enantioenriched biphenols, and yet existing protocols cannot achieve this directly. We address this challenge through the use of enantiopure, sulfonated

Indexed as

StereoisomerismCatalysisLigandsLigands

Identifiers

PMID35969692
PMCPMC9434994

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.