Evidence map›Paper›PMID 35969338›Full record

ReviewJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2023

Electrographic flow mapping for atrial fibrillation: theoretical basis and preliminary observations.

David E Haines, Melissa H Kong, Peter Ruppersberg, Philip Haeusser, Boaz Avitall, Tamas Szili-Torok, Atul Verma

Abstract readReview
In one paragraph

Review in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. A single-center trial of electrographic flow mapping and concomitant voltage mapping in sinus rhythm and atrial fibrillation (FLOW EVAL-AF).Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Trial
  2. Electrographic flow (EGF) mapping reveals sex-based differences in EGF patterns with women concentrated in phenotypes that benefit from EGF-guided ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Electrographic flow mapping of atrial fibrillation.Current opinion in cardiology · 2025
    Review
  9. Article
  10. Article
  11. Navigating the Ebb and Flow of Atrial Fibrillation.JACC. Clinical electrophysiology · 2024
    Article
  12. Advanced Electroanatomic Mapping: Current and Emerging Approaches.Current treatment options in cardiovascular medicine · 2024
    Article
  13. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  14. Electrographic flow mapping of persistent atrial fibrillation: intra- and inter-procedure reproducibility in the absence of 'ground truth'.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  15. Article
  16. Rotor mechanism and its mapping in atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Review
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David E HainesDepartment of Cardiovascular Medicine, Beaumont Hospital, Oakland University William Beaumont School of Medicine, 3601 West 13 Mile Rd., Royal Oaks, MI, 48973, USA. dhaines@beaumont.edu.ORCID http://orcid.org/0000-0002-5592-8338
Melissa H KongAblacon Inc., Wheat Ridge, CO, USA.
Peter RuppersbergAblacon Inc., Wheat Ridge, CO, USA.
Philip HaeusserAblacon Inc., Wheat Ridge, CO, USA.
Boaz AvitallDepartment of Medicine and Bioengineering, University of Illinois, Chicago, IL, USA.
Tamas Szili-TorokDepartment of Cardiology, Electrophysiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Atul VermaSouthlake Regional Health Centre, Division of Cardiology, University of Toronto, 602-581 Davis Drive, Newmarket, Ontario, L3Y 2P6, Canada. atul.verma@utoronto.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ablation strategies remain poorly defined for persistent atrial fibrillation (AF) patients with recurrence despite intact pulmonary vein isolation (PVI). As the ability to perform durable PVI improves, the need for advanced mapping to identify extra-PV sources of AF becomes increasingly evident. Multiple mapping technologies attempt to localize these self-sustained triggers and/or drivers responsible for initiating and/or maintaining AF; however, current approaches suffer from technical limitations. Electrographic flow (EGF) mapping is a novel mapping method based on well-established principles of optical flow and fluid dynamics. It enables the full spatiotemporal reconstruction of organized wavefront propagation within the otherwise chaotic and disorganized electrical conduction of AF. Given the novelty of EGF mapping and relative unfamiliarity of most clinical electrophysiologists with the mathematical principles powering the EGF algorithm, this paper provides an in-depth explanation of the technical/mathematical foundations of EGF mapping and demonstrates clinical applications of EGF mapping data and analyses. Starting with a 64-electrode basket catheter, unipolar EGMs are recorded and processed using an algorithm to visualize the electrographic flow and highlight the location of high prevalence AF "source" activity. The AF sources are agnostic to the specific mechanisms of source signal generation.

Indexed as

Atrial FibrillationCatheter AblationPulmonary VeinsAlgorithmsEpidermal Growth FactorHumansRecurrenceTreatment OutcomeEpidermal Growth FactorAtrial fibrillationCatheter ablationElectrographic flow mappingSignal processing

Identifiers

PMID35969338
PMCPMC10172240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.