Evidence map›Paper›PMID 35969316›Full record

ArticleClinical oral investigations2023

Antimicrobial surface processing of polymethyl methacrylate denture base resin using a novel silica-based coating technology.

Chiaki Tsutsumi-Arai, Kazuhiro Akutsu-Suyama, Yoko Iwamiya, Chika Terada-Ito, Zenji Hiroi, Mitsuhiro Shibayama, Kazuhito Satomura

Abstract read
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Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Evaluation of Colonization byMaterials (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chiaki Tsutsumi-AraiDepartment of Oral Medicine and Stomatology, School of Dental Medicine, Tsurumi University, 2-1-3, Tsurumi, Tsurumi-ku, Yokohama, Kanagawa, 230-8501, Japan. tsutsumi-c@tsurumi-u.ac.jp.
Kazuhiro Akutsu-SuyamaNeutron Science and Technology Center, Comprehensive Research Organization for Science and Society (CROSS), Tokai, Ibaraki, 319-1106, Japan.
Yoko IwamiyaChoetsu Kaken Co., Ltd., Suehiro, Tsurumi, Yokohama, Kanagawa, 230-0045, Japan.
Chika Terada-ItoDepartment of Oral Medicine and Stomatology, School of Dental Medicine, Tsurumi University, 2-1-3, Tsurumi, Tsurumi-ku, Yokohama, Kanagawa, 230-8501, Japan.
Zenji HiroiInstitute for Solid State Physics, University of Tokyo, Kashiwa, Chiba, 277-8581, Japan.
Mitsuhiro ShibayamaNeutron Science and Technology Center, Comprehensive Research Organization for Science and Society (CROSS), Tokai, Ibaraki, 319-1106, Japan.
Kazuhito SatomuraDepartment of Oral Medicine and Stomatology, School of Dental Medicine, Tsurumi University, 2-1-3, Tsurumi, Tsurumi-ku, Yokohama, Kanagawa, 230-8501, Japan.
Tsurumi University · JPComprehensive Research Organization for Science and Society · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study investigated the surface characteristics of denture base resin coatings prepared using a novel silica-based film containing hinokitiol and assessed the effect of this coating on Candida albicans adhesion and growth.

methodsSilica-based coating solutions (control solution; CS) and CS containing hinokitiol (CS-H) were prepared. C. albicans biofilm formed on denture base specimens coated with each solution and these uncoated specimens (control) were analyzed using colony-forming unit (CFU) assay, fluorescence microscopy, and scanning electron microscopy (SEM). Specimen surfaces were analyzed by measuring the surface roughness and wettability and with Fourier-transform infrared (FT-IR) and proton nuclear magnetic resonance (

resultsCS-H and CS-H-1w contained significantly lower CFUs than those present in the control and control-1w, which was also confirmed via SEM. Fluorescence microscopy from the CS-H group identified several dead cells. The values of surface roughness from coating groups were significantly less than those from the control and control-1w. The surface wettability from all coating groups exhibited high hydrophobicity. FT-IR analyses demonstrated that specimens were successfully coated, and

conclusionsA silica-based denture coating that incorporates hinokitiol inhibits C. albicans growth on denture. CLINICAL RELEVANCE: We provide a novel antifungal denture coating which can be helpful for the treatment of denture stomatitis.

Indexed as

Polymethyl MethacrylateSilicon DioxideAntifungal AgentsBiofilmsCandida albicansDenture BasesMaterials TestingMonoterpenesSpectroscopy, Fourier Transform InfraredSurface PropertiesTropoloneAntifungal Agentsbeta-thujaplicinMonoterpenesPolymethyl MethacrylateSilicon DioxideTropoloneC. albicansDentureDenture stomatitisHinokitiolSilica-resin coating

Identifiers

PMID35969316
OpenAlexW4291901873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.