SynthesisANZ journal of surgery2022
Laparoscopic versus open surgery for elderly patients with colorectal cancer: a systematic review and meta-analysis of matched studies.
Synthesis in ANZ journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Clinical Practice Guideline: Colorectal Cancer—Diagnosis, Treatment, Prevention, and Long-Term Follow-Up Care.Deutsches Arzteblatt international · 2025Guideline
- Meta-analysis of robotic-assisted NOSE versus traditional TWSR in colorectal cancer surgery: postoperative outcomes and efficacy.BMC surgery · 2024Pooled it
- Colorectal Cancer Surgery: Laparoscopic vs. Robotic Approaches-A Review of the Literature.Journal of clinical medicine · 2026Review
- The Impact of Low Back Pain on the Self-Assessed Health-Related Quality of Life in Colostomy Patients-A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Impact of Age on Surgical and Oncologic Outcomes After Colorectal Cancer Resection in Selected Patients Undergoing Primary Anastomosis: A Retrospective Propensity-Matched Cohort Study.Cancer medicine · 2026Article
- Acute Gallbladder Volvulus in a 93-Year-Old High-Risk Patient: A Case Report.The American journal of case reports · 2026Article
- Automated surgical instrument recognition in laparoscopic cholecystectomy videos: a novel two-step deep learning approach with virtual image synthesis.Surgical endoscopy · 2026Article
- Surgical treatment strategy for elderly patients with esophageal cancer in the new era: a narrative review.Surgery today · 2025Review
- Colonic stenting for colorectal cancer: stoma avoidance with acceptable radiation exposure.Clinical endoscopy · 2025Article
- Impact of autonomic nerve-oriented anatomical laparoscopic surgery on recovery in patients with colorectal cancer.World journal of gastrointestinal surgery · 2025Article
- Article
- Evaluation and analysis of neurocognitive dysfunction in patients with colorectal cancer after radical resection: A retrospective study.World journal of gastrointestinal surgery · 2024Article
- Comparisons of postoperative outcomes of laparoscopic versus open surgery using inverse probability of treatment weighting analysis: an evidence from Iran.BMC surgery · 2024Article
- Advancements in colorectal cancer research: Unveiling the cellular and molecular mechanisms of neddylation (Review).International journal of oncology · 2024Review
- A virtual simulation approach to assess the effect of trocar-site placement and scar characteristics on the abdominal wall biomechanics.Scientific reports · 2024Article
- Sterile Inflammatory Response and Surgery-Related Trauma in Elderly Patients with Subtrochanteric Fractures.Biomedicines · 2024Article
- Comparative study of robotic-assisted vs. laparoscopic surgery for colorectal cancer: a single-center experience.Frontiers in oncology · 2024Article
- Outcomes of Laparoscopic Surgery in Very Elderly Patients with Colorectal Cancer: A Survival Analysis and Comparative Study.Journal of clinical medicine · 2023Article
- Evaluation of the advantages of robotic versus laparoscopic surgery in elderly patients with colorectal cancer.BMC geriatrics · 2023Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo compare clinical and survival outcomes between laparoscopic versus open surgery in elderly colorectal cancer patients.
methodsPubMed, Embase and Scopus databases were systematically searched. The review included studies that were either randomized controlled trials (RCTs) or observational in design. STATA was used for statistical analysis.
resultsThe meta-analysis was conducted with 24 studies. Compared with elderly subjects with open surgery, those undergoing laparoscopic surgery had a lower risk of mortality (within 3 months postoperatively) (RR 0.70, 95% CI: 0.53, 0.94). The long-term overall survival (HR 0.96, 95% CI: 0.89, 1.04), disease-free survival (HR 1.02, 95% CI: 0.93, 1.13), risk of recurrence (RR 1.44, 95% CI: 0.90, 2.30) and readmission (RR 1.11, 95% CI: 0.88, 1.40) rates were statistically similar in both the groups. The operative time (in minutes) was higher (WMD 30.37, 95% CI: 17.75, 43.0) and the blood loss (in ml) was lower (WMD -78.85, 95% CI: -101.96, -55.75) in those undergoing laparoscopic surgery. The length of hospital stay (in days) (WMD -2.53, 95% CI: -3.11, -1.95) and the time of return of bowel movements (in days) (WMD -1.06, 95% CI: -1.20, -0.93) was lower in those with laparoscopic surgery. The pooled risk of complications was lower in those with laparoscopic surgery (RR 0.66, 95% CI: 0.60, 0.74), compared with open surgery.
conclusionsFindings suggest that in elderly subjects with colorectal cancer, laparoscopic surgery appears to be more beneficial than open surgery and should be prioritized, subject to the availability of required technical skills and facilities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.