Evidence map›Paper›PMID 35968879›Full record

ArticleThe Journal of infectious diseases2022

Respiratory Syncytial Virus Burden and Healthcare Utilization in United States Infants <1 Year of Age: Study of Nationally Representative Databases, 2011-2019.

Mina Suh, Naimisha Movva, Xiaohui Jiang, Heidi Reichert, Lauren C Bylsma, Jon P Fryzek, Christopher B Nelson

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 4 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mina SuhEpidStrategies, a Division of ToxStrategies, Rockville, Maryland, USA.ORCID 0000-0002-9557-4933
Naimisha MovvaEpidStrategies, a Division of ToxStrategies, Rockville, Maryland, USA.ORCID 0000-0001-9300-5473
Xiaohui JiangEpidStrategies, a Division of ToxStrategies, Rockville, Maryland, USA.
Heidi ReichertEpidStrategies, a Division of ToxStrategies, Rockville, Maryland, USA.
Lauren C BylsmaEpidStrategies, a Division of ToxStrategies, Rockville, Maryland, USA.ORCID 0000-0002-3091-6090
Jon P FryzekEpidStrategies, a Division of ToxStrategies, Rockville, Maryland, USA.ORCID 0000-0003-4089-3846
Christopher B NelsonSanofi, Swiftwater, Pennsylvania, USA.ORCID 0000-0003-1046-7635
Sanofi (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) is the leading cause of hospitalizations in United States infants aged <1 year, but research has focused on select populations.

methodsNational (Nationwide) Inpatient Sample and National Emergency Department (ED) Sample data (2011-2019) were used to report RSV hospitalization (RSVH), bronchiolitis hospitalization (BH), and ED visit counts, percentage of total hospitalizations/visits, and rates per 1000 live births along with inpatient mortality, mechanical ventilation (MV), and total charges (2020 US dollars).

resultsAverage annual RSVH and RSV ED visits were 56 927 (range, 43 845-66 155) and 131 999 (range, 89 809-177 680), respectively. RSVH rates remained constant over time (P = .5), whereas ED visit rates increased (P = .004). From 2011 through 2019, Medicaid infants had the highest average rates (RSVH: 22.3 [95% confidence interval {CI}, 21.5-23.1] per 1000; ED visits: 55.9 [95% CI, 52.4-59.4] per 1000) compared to infants with private or other/unknown insurance (RSVH: P < .0001; ED visits: P < .0001). From 2011 through 2019, for all races and ethnicities, Medicaid infants had higher average RSVH rates (up to 7 times) compared to infants with private or other/unknown insurance. RSVH mortality remained constant over time (P = .8), whereas MV use (2019: 13% of RSVH, P < .0001) and mean charge during hospitalization (2019: $21 513, P < .0001) increased. Bronchiolitis patterns were similar.

conclusionsThis study highlights the importance of ensuring access to RSV preventive measures for all infants.

Indexed as

BronchiolitisRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsHumansInfantInfant, NewbornInfant, PrematurePatient Acceptance of Health CareUnited Statesbirth monthbronchiolitis hospitalizationsemergency departmentinfantsMedicaidrespiratory syncytial virusRSVRSV hospitalizations

Identifiers

PMID35968879
PMCPMC9377028
OpenAlexW4226217645

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.