ArticleDisease markers2022
Hepatic Steatosis Index and the Risk of Type 2 Diabetes Mellitus in China: Insights from a General Population-Based Cohort Study.
Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Association between hepatic steatosis index and gallstones in US adults: A cross-sectional study of NHANES 2017-2020.Medicine · 2026Article
- Non-Invasive Tests for the Detection of MASLD: Biomarkers and Imaging for Staging Steatosis, MASH, and Fibrosis.International journal of general medicine · 2026Review
- First-trimester fatty liver index and hepatic steatosis index independently predict gestational diabetes risk: a prospective cohort study.Frontiers in nutrition · 2026Article
- The effect of hepatic steatosis index on prediabetes: A large-scale retrospective cohort study.Scientific reports · 2025Article
- Longitudinal correlation between cumulative remnant cholesterol inflammatory index and incident diabetes.Diabetology & metabolic syndrome · 2025Article
- A cross-sectional analysis of remnant cholesterol-diabetes association in US adults.Scientific reports · 2025Article
- Association between liver fibrosis scores and cardiovascular disease in elderly based on NHANES 1999-2018.Scientific reports · 2025Article
- Non-linear relationship between the hepatic steatosis index and glycemic progression: evidence from a large-scale retrospective cohort study in a Chinese population.BMC gastroenterology · 2025Article
- First trimester hepatic steatosis index as a predictor of gestational diabetes mellitus: a cohort study in Northwestern China.Scientific reports · 2025Article
- Application of the C-reactive protein-triglyceride glucose index in predicting the risk of new-onset diabetes in the general population aged 45 years and older: a national prospective cohort study.BMC endocrine disorders · 2025Article
- AIP, fatty liver, and HbA1c as modifiers of the C-index and diabetes risk relationship.Lipids in health and disease · 2025Article
- Association of estimated small dense low-density lipoprotein cholesterol with diabetes mellitus: a large-scale multicenter retrospective cohort study.BMC endocrine disorders · 2025Article
- Association between hepatic steatosis index and glucose status conversion from impaired fasting glucose base on Chinese adults: a cohort study from real-world.European journal of medical research · 2025Article
- Intake of sodium and potassium, sodium-potassium intake ratio, and their relation to the risk of diabetes mellitus.Scientific reports · 2025Article
- Nonlinear relationship between hepatic steatosis index and reversion to normal glucose regulation in Chinese adults with prediabetes.Scientific reports · 2025Article
- Relationship between metabolically healthy overweight/obesity and risk of type 2 diabetes in different ethnicity: a prospective cohort study in southwest China.BMC public health · 2024Article
- Lipid accumulation product and type 2 diabetes risk: a population-based study.BMC endocrine disorders · 2024Article
- Association of white blood cell count to mean platelet volume ratio with type 2 diabetic peripheral neuropathy in a Chinese population: a cross-sectional study.BMC endocrine disorders · 2024Article
- Association of Hepatic Steatosis and Fibrosis Indices With Insulin Sensitivity and Inflammation in the POP-ABC Study.Journal of the Endocrine Society · 2024Article
- Association between changes in body composition and progression of liver fibrosis in patients with type 2 diabetes mellitus.Frontiers in nutrition · 2024Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: In the Chinese population, we looked at the relationship between the hepatic steatosis index (HSI) and the risk of type 2 diabetes mellitus (T2DM). Methods: To evaluate the association between HSI and the risk of T2DM, Cox regression models were employed. Hazard ratios (HR) and 95 percent confidence intervals (CI) were computed. A stratified analysis with interaction testing was also carried out. Additionally, we evaluated the incremental predictive value of the HSI over the established risk factors using the C-statistic, the IDI, and the NRI. Results: During a median follow-up period of 2.97 years, 433 (1.97%) participants developed new-onset T2DM. The smoothing curve fit plot showed a positive correlation between HSI and the risk of T2DM. After adjusting for all noncollinear variables, the risk of T2DM increased by 62% for every 1 standard deviation (SD) increase in HSI. Subgroup analysis indicated that higher HSI levels were associated with a higher risk of T2DM in those aged < 40 years. The addition of HSI enhanced the reclassification and discrimination of established risk factors, with an IDI of 0.027 and an NRI of 0.348 (both Conclusion: Our findings suggest that an elevated HSI is substantially associated with a greater risk of T2DM in the Chinese population. HSI has the potential to be an available and supplementary monitoring method for the management of T2DM risk stratification in the Chinese population.
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