Evidence map›Paper›PMID 35968404›Full record

ArticleCurrent behavioral neuroscience reports2021

Neural and Behavioral Correlates of Impaired Insight and Self-Awareness in Substance Use Disorder.

Crista E Maracic, Scott J Moeller

Open access · greenAbstract read
In one paragraph

Article in Current behavioral neuroscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Tobacco Images Choice and its Association With Craving and Dependence in People Who Smoke Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  9. Neural Correlates of Metacognition Impairment in Opioid Addiction.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Candidate biomarkers in psychiatric disorders: state of the field.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Crista E MaracicRenaissance School of Medicine at Stony Brook University, Stony Brook, NY, 11794.
Scott J MoellerRenaissance School of Medicine at Stony Brook University, Stony Brook, NY, 11794.
Stony Brook School · US

Funding

Neurocircuitry of clinical insight predicting relapse outcomes in opioid addictionR01DA051420 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI MOELLER, SCOTT J · 2020 to 2025
$2.9M
Neural, endocrine, and behavioral markers of psychosocial stress predicting drug use outcomes in human opioid addictionR01DA049733 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI MOELLER, SCOTT J · 2021 to 2025
$2.6M
Neural and neurochemical correlates of metacognition impairment in opioid addictionR21DA048196 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI MOELLER, SCOTT J · 2020 to 2021
$439k
NIDA NIH HHS R01 DA049733NIDA NIH HHS R01 DA051420NIDA NIH HHS R21 DA048196
6 · The paper itself

Abstract

Purpose of Review: Clinical insight is an emerging interest in substance use disorder research, but is difficult to study empirically. We reviewed recent research examining the behavioral and neural correlates of several psychological processes tapping into self-awareness that may in turn contribute to insight. Recent Findings: Individuals with substance use disorder exhibit deficits in self-monitoring (especially self-report / behavior dissociations), metacognition, alexithymia, readiness for behavior change, and interoception. Behavioral impairments have been further linked to neural abnormalities in a diverse network of brain regions encompassing cortical midline areas, insula, and frontal cortex, among others. Various treatment modalities may target these deficits, though corresponding effects on neural circuitry remain to be determined. Summary: Compromised insight in substance use disorder may be relevant to a constellation of behaviors that suggest a lack of behavioral awareness linked to drug use. Future work needs to refine and advance the measurements, continuing to investigate insight problems in addiction that may become important therapeutic targets.

Indexed as

fMRIInsightInteroceptionMetacognitionSelf-AwarenessSelf-MonitoringSubstance Use Disorder

Identifiers

PMID35968404
PMCPMC9374000
OpenAlexW3211655432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.