Evidence map›Paper›PMID 35968360›Full record

ArticleFrontiers in neuroscience2022

Cases report: MRI findings of asymptomatically familial subependymal heterotopia with filamin A gene abnormality.

Bin Lv, Yushan Zhou, Jianguang Zeng, Ling Wang, Fumin Zhao, Huizhu Chen, Xuesheng Li, Yu Song, Mei Xiao, Zhiyong Ding and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Bin LvDepartment of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Yushan ZhouDepartment of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu, China.
Jianguang ZengSchool of Economics and Business Administration, Chongqing University, Chongqing, China.
Ling WangDepartment of Ultrasound, West China Second University Hospital, Sichuan University, Chengdu, China.
Fumin ZhaoDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, China.
Huizhu ChenDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, China.
Xuesheng LiDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, China.
Yu SongDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, China.
Mei XiaoDepartment of Medical Imaging, Qujing Maternal and Child Health Care Hospital, Kunming University of Science and Technology, Qujing, China.
Zhiyong DingDepartment of Medical Imaging, Qujing Maternal and Child Health Care Hospital, Kunming University of Science and Technology, Qujing, China.
Bochao ChengDepartment of Radiology, West China Second University Hospital, Sichuan University, Chengdu, China.
West China Second University Hospital of Sichuan University · CNSichuan University · CNKunming University of Science and Technology · CNChongqing University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subependymal heterotopia (SEH) is a rare neuronal migration disorder consisting of gray matter nodules along the lateral ventricular walls and is often associated with other brain malformations. Despite most SEH cases showing epilepsy during their lifetimes, very few patients with asymptomatically familial SEH tend to cause misdiagnosis or missed diagnosis. We present four familial SEH cases without any positive symptoms and medical history, including two fetuses, who were diagnosed by MRI and confirmed by genetic testing with mutation of filamin A. This report emphasizes the role of MRI in the recognition of SEH at an early age of gestation and in asymptomatically familial SEH. MRI provides a fast, repeatable, reliable, and cheap choice for detecting and screening familial SEH.

Indexed as

asymptomaticcase reportfilamin Amagnetic resonance imagingsubependymal heterotopia

Identifiers

PMID35968360
PMCPMC9364927
OpenAlexW4288067808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.