Evidence map›Paper›PMID 35968313›Full record

SynthesisFrontiers in neurology2022

Brain Activities Responding to Acupuncture at ST36 (

Haoming Huang, Xiaomei Yue, Xi Huang, Wenjie Long, Shangyu Kang, Yawen Rao, Jingchun Zeng, Junling Zuo, Lin Wang, Hongjuan Li and 3 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Objectivization study of acupunctureFrontiers in neuroscience · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. The effect of acupuncture at theFrontiers in integrative neuroscience · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Haoming HuangThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xiaomei YueThe First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xi HuangDepartment of Geriatrics, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
Wenjie LongDepartment of Geriatrics, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
Shangyu KangDepartment of Radiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Yawen RaoDepartment of Radiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Jingchun ZengDepartment of Rehabilitation, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Junling ZuoDepartment of Emergency, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Lin WangDepartment of Emergency, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Hongjuan LiThe First Comprehensive Department, The Second Affiliated Hospital, Guangzhou University of Chinese Medicine (Guangdong Province Hospital of Chinese Medicine), Guangzhou, China.
Yeqing WangDepartment of Chinese Medicine, The First Affiliated Hospital, School of Clinical Medicine of Guangdong Pharmaceutical University, Guangzhou, China.
Shijun QiuDepartment of Radiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Weixuan ZhaoDepartment of Chinese Medicine, The First Affiliated Hospital, School of Clinical Medicine of Guangdong Pharmaceutical University, Guangzhou, China.
First Affiliated Hospital of Guangzhou University of Chinese Medicine · CNGuangdong Pharmaceutical University · CNGuangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Stomach 36 (ST36, Methods: Literature searches were conducted on online databases, including MEDLINE, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang database, WeiPu database, and China Biology Medicine, for task-based fMRI studies of acupuncture at ST36 in healthy subjects. Brain regions activated by ST36 acupuncture were systematically evaluated and subjected to seed-based Results: A total of sixteen studies, involving a total of 401 right-handed healthy participants, that satisfied the inclusion criteria were included in the present meta-analysis. Meta-analysis showed that acupuncturing on ST36 positively activates the opercular part of the right inferior frontal gyrus (IFG.R), left superior temporal gyrus (STG.L), and right median cingulate/paracingulate gyri (MCG.R) regions. Needle retention time in an acupuncture session positively correlates with the activation of the left olfactory cortex, as shown in meta-regression analysis. Subgroup analysis revealed that EA stimulation may be a source of heterogeneity in the pooled results. Functional network mappings showed that the activated areas were mapped to the auditory network and salience network. Further functional decoding analysis showed that acupuncture on ST36 was associated with pain, secondary somatosensory, sound and language processing, and mood regulation. Conclusion: Acupuncture at ST36 in healthy individuals positively activates the opercular part of IFG.R, STG.L, and MCG.R. The left olfactory cortex may exhibit positive needle retention time-dependent activities. Our findings may have clinical implications for acupuncture in analgesia, language processing, and mood disorders. Systematic Review Registration: https://inplasy.com/inplasy-2021-12-0035.

Indexed as

acupuncturebrain activationST36 (zusanli)systematic reviewtask-based fMRI

Identifiers

PMID35968313
PMCPMC9373901
OpenAlexW4286672056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.