Evidence map›Paper›PMID 35968291›Full record

SynthesisFrontiers in neurology2022

Rhythmic auditory stimulation promotes gait recovery in Parkinson's patients: A systematic review and meta-analysis.

Xiaofan Ye, Ling Li, Rong He, Yizhen Jia, Waisang Poon

Registry-linked trialOpen access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05733819 (Responders to Metronome-based Rhythmic Auditory Cueing in Parkinson Disease), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05733819 phase1completednot on this mapstarted 2023, after this paper: background citation

Responders to Metronome-based Rhythmic Auditory Cueing in Parkinson Disease

TypeinterventionalSponsorBoston University Charles River CampusRan2023 to 2023Enrolled31ConditionsParkinson DiseaseArmsSubject-specific optimized RAS, Active Walking
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Xiaofan YeNeuromedicine Center, University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Ling LiNeuromedicine Center, University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Rong HePhysiotherapy Department, University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Yizhen JiaCore Laboratory, University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Waisang PoonNeuromedicine Center, University of Hong Kong Shenzhen Hospital, Shenzhen, China.
University of Hong Kong · HKUniversity of Hong Kong - Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Using rhythmic auditory stimulation (RAS) to improve gait disturbance in Parkinson's disease (PD) is an available treatment option, yet a consensus on its effectiveness remains controversial. We summarized the effects of RAS on gait, functional activity and quality of life in PD patients through a systematic review and meta-analysis. Methods: PubMed, Embase, Web of Science, Medline, and Cochrane Library databases were initially searched to identify relevant literature up to August 2021. Next, the methodological quality of eligible comparative studies was assessed by the Physiotherapy Evidence Database Scale. The treatment effects to clinical outcome in relation to gait, motor activities, and quality of life were analyzed. Results: A total of 18 studies consisted of 774 subjects were included in this meta-analysis. Comparing with the control group, RAS had significantly increased stride length ( Conclusion: In this meta-analysis of 18 randomized controlled trials, we have demonstrated that RAS improves the general motor functions (UPDRS-III), particularly in gait, mobility and quality of life, in patients with Parkinson's disease.

Indexed as

gaitmeta-analysismobilityParkinson's patientsrhythmic auditory stimulation

Identifiers

PMID35968291
PMCPMC9366143
OpenAlexW4288431147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.