Evidence map›Paper›PMID 35968053›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2022

Corneal Epithelium Asymmetry in Children With Atopy: The Effect of Hand Dominance.

Tomás Loureiro, Sandra Rodrigues-Barros, Ana Rita Carreira, Filipe Gouveia-Moraes, Pedro Carreira, Ana Vide Escada, Paul Campos, Inês Machado, Nuno Campos, Timothy J Archer and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Tomás LoureiroOphthalmology Department, Hospital Garcia de Orta, Almada, Portugal.ORCID 0000-0001-7949-7248
Sandra Rodrigues-BarrosOphthalmology Department, Hospital Garcia de Orta, Almada, Portugal.
Ana Rita CarreiraOphthalmology Department, Hospital Garcia de Orta, Almada, Portugal.
Filipe Gouveia-MoraesOphthalmology Department, Hospital Garcia de Orta, Almada, Portugal.ORCID 0000-0003-0584-9735
Pedro CarreiraOphthalmology Department, Hospital Garcia de Orta, Almada, Portugal.ORCID 0000-0003-3376-7040
Ana Vide EscadaOphthalmology Department, Hospital Garcia de Orta, Almada, Portugal.
Paul CamposOphthalmology Department, Hospital Garcia de Orta, Almada, Portugal.
Inês MachadoOphthalmology Department, Hospital Garcia de Orta, Almada, Portugal.
Nuno CamposOphthalmology Department, Hospital Garcia de Orta, Almada, Portugal.
Timothy J ArcherLondon Vision Clinic, London, UK.
Dan Z ReinsteinLondon Vision Clinic, London, UK.ORCID 0000-0001-6747-7311
Renato AmbrósioFederal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0001-6919-4606
Hospital Garcia de Orta · PTLondon Vision Clinic · GBUniversidade Federal do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the effect of eye rubbing on the epithelial thickness profile in tomographically normal corneas by AS-OCT and to compare right and left eyes in right-handed children. Methods: Thirty right-handed boys (mean age 11.2 years) with ocular allergy and history of eye rubbing were evaluated using Scheimpflug (Pentacam HR, Oculus Wetzlar, Germany) and anterior segment optical coherence tomography. Epithelial thickness (ET) and full corneal thickness (CT) parameters were compared between right and left eyes with a non-parametric Mann-Whitney test. A p-value lower than 0.05 was considered for statistical significance. Results: No eyes had topometric nor tomographic criteria for keratoconus. The min-max ET was lower in right eyes (-2.8 µm vs -3.5; p = 0.02). The difference between inferior and superior (I-S) octants was lower in right eyes (1.1 µm vs 1.9 µm; p = 0.03) as a result of inferotemporal thinning. The highest ET difference was registered between nasal and temporal octants and was more pronounced in the right eyes (2 µm vs 3.1 µm; p < 0.001). Conclusion: AS-OCT analyses reveal different epithelial thickness patterns between the eyes in young atopic patients, likely eye rubbers. Inferior and temporal epithelial thickness seem to be more affected by thinning in the eye on the side of the dominant hand.

Indexed as

AS-OCTepithelial thicknesseye rubbingkeratoconuspediatrics

Identifiers

PMID35968053
PMCPMC9365055
OpenAlexW4289979131

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.