ReviewFrontiers in aging neuroscience2021
Inhibitory Control in Aging: The Compensation-Related Utilization of Neural Circuits Hypothesis.
Review in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- A systematic review of neuroimaging studies of adults aged 35 and older with clinical, symptomatic and genetic risk for attention-deficit/hyperactivity disorder.Dialogues in clinical neuroscience · 2026Pooled it
- The effects of aerobic exercise on goal-directed attention and inhibitory control in individuals with high trait anxiety: an EEG study.BMC psychology · 2025Trial
- Trial
- Adults up to 80 years old maintain effective movement planning when facing complex body dynamics.GeroScience · 2026Article
- Cortical activation, gait performance, and muscle activation during dual-task walking in older adults with mild cognitive impairment.BMC geriatrics · 2026Article
- Article
- Age-related neural inefficiency: fNIRS evidence of prefrontal hyperactivation during emotional response inhibition.GeroScience · 2026Article
- Mapping the Digital Mind: A Meta-Analysis of EEG Biomarkers in Cognition, Emotion, and Mental Health.Brain sciences · 2026Review
- β-Bursting as a Sensitive Neural Marker of Inhibitory Control in Healthy Older Adults: A Linear Mixed-Effects Modeling and Threshold-Free Cluster Approach.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Association of 24-hour movement guideline adherence with inhibitory control in older adults: the mediating role of general self-efficacy.Frontiers in psychology · 2026Article
- The ageing brain: Cortical overactivation - How does it evolve?The Journal of physiology · 2026Review
- The effect of Alzheimer's biomarker positivity on neuropsychological networks.Brain communications · 2026Article
- Are brief batteries able to identify aphasia in elderly people? A study with the ABLA Battery.CoDAS · 2026Article
- A comprehensive review on adaptive plasticity and recovery mechanisms post-acquired brain injury.Neuroprotection (Chichester, England) · 2025Review
- Brain functional connectivity characteristics at various levels of inhibitory function in elderly individuals with cognitive impairment.Scientific reports · 2025Article
- Global Cognition and Inhibition as Predictors of Dynamic Balance in Aging Populations: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Cohen-mansfield agitation inventory total score as a measure of agitation and aggression in Alzheimer's disease: A factor analysis.International psychogeriatrics · 2025Article
- Neuroanatomical Changes in the Stopping Network Across the Adult Lifespan Assessed With Quantitative and Diffusion MRI.Human brain mapping · 2025Article
- Age-invariant benefits of spatiotemporal predictions amidst distraction during dynamic visual search.Scientific reports · 2025Article
- Age-related differences in eye blink-related neural activity and functional connectivity during driving.Heliyon · 2025Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As one of the core executive functions, inhibitory control plays an important role in human life. Inhibitory control refers to the ability to suppress task irrelevant information both internally and externally. Modern cognitive neuroscience has extensively investigated the neural basis of inhibitory control, less is known about the inhibitory control mechanisms in aging. Growing interests in cognitive declines of aging have given raise to the compensation-related utilization of neural circuits hypothesis (CRUNCH). In this review, we survey both behavioral, functional, and structural changes relevant to inhibitory control in aging. In line with CRUNCH, we found that older adults engage additional brain regions than younger adults when performing the same cognitive task, to compensate for declining brain structures and functions. Moreover, we propose CRUNCH could well take functional inhibitory deficits in older adults into account. Finally, we provide three sensible future research directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.