Evidence map›Paper›PMID 35967881›Full record

ArticleEuropean journal of radiology open2022

Imaging features of toxicities associated with immune checkpoint inhibitors.

Babina Gosangi, Lacey McIntosh, Abhishek Keraliya, David Victor Kumar Irugu, Akshay Baheti, Ashish Khandelwal, Richard Thomas, Marta Braschi-Amirfarzan

Abstract read
In one paragraph

Article in European journal of radiology open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Checkpoint Inhibitor-Induced Colitis: From Pathogenesis to Management.International journal of molecular sciences · 2023
    Review
  17. Article
  18. Review
  19. Review
  20. What's new in cancer and molecular imaging.European journal of radiology open · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Babina GosangiDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Lacey McIntoshDepartment of Radiology, University of Massachusetts, Worcester, MA, USA.
Abhishek KeraliyaDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
David Victor Kumar IruguMagnus Hospital, Hyderabad, India.
Akshay BahetiTata Memorial Hospital, Mumbai, India.
Ashish KhandelwalDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Richard ThomasDepartment of Radiology, Lahey Health System, Burlington, MA, USA.
Marta Braschi-AmirfarzanDepartment of Radiology, Lahey Health System, Burlington, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The past decade has witnessed a change in landscape of cancer management with the advent of precision oncology. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and have played an important role in improving patient survival. While the patients are living longer, treatment with ICIs are sometimes associated with adverse effects, some of which could be fatal. Radiologists can play a crucial role by early identification of some of these adverse effects during restaging scans. Our paper focuses on the imaging features of commonly occurring ICI toxicities based on organ system.

Indexed as

AIP, acute interstitial pneumonitisARDS, acute respiratory distress syndromeColitisCTCAE, Common Terminology Criteria for Adverse EventsCTLA-4 inhibitor, Cytotoxic T-lymphocyte antigen- 4 inhibitorFDA, Food and Drug AdministrationHepatitisICI, Immune check point inhibitorImmune check point inhibitors toxicityirAE, immune-related adverse eventLGE, late Gadolinium enhancementNSCLC, non-small cell lung cancerNSIP, non-specific interstitial pneumoniaOP, organizing pneumoniaPancreatitisPD-1 inhibitor, programmed cell death-1 inhibitorPD-L1 inhibitor, programmed cell death ligand-1 inhibitorPFS, progression free survivalPneumonitisRRP, radiation recall pneumonitis

Identifiers

PMID35967881
PMCPMC9372737

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.