Evidence map›Paper›PMID 35967803›Full record

SynthesisFrontiers in nutrition2022

Association between dietary acid load and cancer risk and prognosis: An updated systematic review and meta-analysis of observational studies.

Ran Wang, Zhao-Yan Wen, Fang-Hua Liu, Yi-Fan Wei, He-Li Xu, Ming-Li Sun, Yu-Hong Zhao, Ting-Ting Gong, Hui-Han Wang, Qi-Jun Wu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Dietary acid load in health and disease.Pflugers Archiv : European journal of physiology · 2024
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ran WangDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Zhao-Yan WenDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Fang-Hua LiuDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Yi-Fan WeiDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
He-Li XuDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Ming-Li SunDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Yu-Hong ZhaoDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.
Ting-Ting GongDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Hui-Han WangDepartment of Hematology, Shengjing Hospital of China Medical University, Shenyang, China.
Qi-Jun WuDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological studies have suggested that dietary acid load (DAL) might be related to the risk and prognosis of cancer, whereas the evidence is contentious. Several high-quality observational studies have been published following a prior systematic review with only one study included. Consequently, we conducted an updated systematic review and meta-analysis to comprehensively investigate the relationship between DAL and cancer risk and prognosis. A systematic literature search was conducted in the PubMed, Embase, and Web of Science databases from inception to 26 October 2021. Summary relative risks (RRs) with 95% CIs were calculated using a random-effects model. Publication bias, subgroup, meta-regression, and sensitivity analyses were also conducted. Ten observational studies (six cohorts and four case-control studies) with 227,253 participants were included in this systematic review and meta-analysis. The summary RRs revealed a statistically significant associations between DAL and cancer risk (RR = 1.58, 95% CI = 1.23-2.05,

Indexed as

cancerdietary acid loadmeta-analysisprognosisrisksystematic review

Identifiers

PMID35967803
PMCPMC9365077

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.