Evidence map›Paper›PMID 35967584›Full record

ArticleFrontiers in pediatrics2022

Clinical presentation of pediatric patients with symptomatic SARS-CoV-2 infection during the first months of the COVID-19 pandemic in a single center in Mexico City.

Ranferi Aragón-Nogales, Jessie Zurita-Cruz, Guillermo Vázquez-Rosales, Rafael Arias-Flores, Claudia Gómez-González, Victoria Montaño-Luna, Mariana Sámano-Aviña, Daniel Pacheco-Rosas, Eric Flores-Ruiz, Miguel Villasís-Keever and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Systematic review with meta-analysis of active herpesvirus infections in patients with COVID-19: Old players on the new field.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ranferi Aragón-NogalesInfectious Diseases Department, Pediatric Hospital National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Jessie Zurita-CruzFaculty of Medicine, National Autonomous University of Mexico, Pediatric Hospital Federico Gómez, Mexico City, Mexico.
Guillermo Vázquez-RosalesInfectious Diseases Department, Pediatric Hospital National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Rafael Arias-FloresHospital Epidemiology Division, Pediatric Hospital National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Claudia Gómez-GonzálezHospital Epidemiology Division, Pediatric Hospital National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Victoria Montaño-LunaInfectious Diseases Department, Pediatric Hospital National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Mariana Sámano-AviñaInfectious Diseases Department, Pediatric Hospital National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Daniel Pacheco-RosasInfectious Diseases Department, Pediatric Hospital National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Eric Flores-RuizInfectious Diseases Department, Pediatric Hospital National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Miguel Villasís-KeeverAnalysis and Synthesis of the Evidence Research Unit, National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Guadalupe Miranda-NovalesAnalysis and Synthesis of the Evidence Research Unit, National Medical Center XXI Century, Mexican Institute of Social Security, Mexico City, Mexico.
Mexican Social Security Institute · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The clinical spectrum of COVID-19 is broad, from asymptomatic to severe cases and death. The objective of this study is to analyze the clinical course of patients attended during the first months of the SARS-CoV-2 pandemic in a third-level pediatric hospital. Methods: Results: A total of 697 patients met the operational definition of viral respiratory disease or suspected cases of COVID-19 and underwent real-time reverse transcription polymerase chain reaction (rRT-PCR) SARS-CoV-2 testing. Patients with a positive result were included. Of the 181 patients (26%), 121 (66.8%) had mild disease and were treated as outpatients and 60 (33.1%) were hospitalized. A total of six patients met the criteria for multisystem inflammatory syndrome in children (MIS-C). Of the 60 inpatients, 65% were males, and 82% had one or more comorbidities. The main comorbidities were cancer (42%) and overweight (15%). The median hospital stay was 9 days. The inpatients had a higher frequency of fever, general malaise, dyspnea, chills, polypnea, and cyanosis than the outpatients ( Conclusion: Hospital mortality is high, especially in children with comorbidities. Despite 2 years having passed since the beginning of the COVID-19 pandemic, the epidemiological and clinical data on children are still helpful to improve their prognosis.

Indexed as

adolescentschildrenCOVID-19Latin AmericamorbiditymortalityprognosisSARS-CoV-2

Identifiers

PMID35967584
PMCPMC9366046
OpenAlexW4288439590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.