SynthesisFrontiers in pediatrics2022
Azygos vein preservation is feasible and beneficial in esophageal atresia with tracheoesophageal fistula: A meta-analysis of randomized controlled trials.
Synthesis in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Preservation of the azygos vein versus ligation of the azygos vein during primary surgical repair of congenital esophageal atresia.The Cochrane database of systematic reviews · 2025Pooled it
- Azygos vein preservation revisited: impact on early outcomes after repair of esophageal atresia/tracheoesophageal fistula in newborns.Updates in surgery · 2023Trial
- Early postoperative inflammatory markers associated with anastomotic leakage after repair of congenital esophageal atresia.BMC pediatrics · 2026Article
- Evaluation of surgical outcomes of thoracoscopic esophageal atresia repair with and without preservation of azygos vein: a retrospective cohort study.Pediatric surgery international · 2026Article
- Outcomes and challenges in the management of esophageal atresia and/or tracheoesophageal fistula: insights from Turkish Esophageal Atresia Registry.World journal of pediatric surgery · 2025Review
- Esophageal atresia with and without tracheoesophageal fistula: a 2016-2024 single-center cohort study in Saudi Arabia stratified by gap length.World journal of pediatric surgery · 2025Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Esophageal atresia (EA) with tracheoesophageal fistula (TEF) is a common congenital anomaly. It is still unknown whether azygos vein preservation will increase the difficulty or time of operation and reduce the quality of anastomosis. Thus, we conducted this meta-analysis to explore the puzzle. Methods: Two researchers independently searched the databases. Randomized controlled trials were included if these studies applied thoracotomy to perform operations and compared the outcomes in patients with EA/TEF between azygos vein preservation groups and azygos vein ligation groups. The Jadad score was used to assess the quality of the included studies. Statistical heterogeneity was evaluated using the Results: Four studies involving 286 patients were included. The pooled estimates indicated that preservation of the azygos vein decreased the incidence of anatomic leakage with a pooled risk ratio (RR) of 0.54 (95% CI 0.29-0.99, Conclusions: This research certifies that preservation of the azygos vein is able to reduce the prevalence of anastomotic leakage and mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.