Evidence map›Paper›PMID 35967420›Full record

ReviewFrontiers in immunology2022

Pathophysiology of RAGE in inflammatory diseases.

Hanbing Dong, Yue Zhang, Yu Huang, Hui Deng

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07728877 (A Culture-tailored Plant-based Dietary Intervention in Taiwan), which is not on this map. Cited by 155 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 2 pooled it
24.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07728877 nacompletednot on this mapstarted 2023, after this paper: background citation

A Culture-tailored Plant-based Dietary Intervention in Taiwan: A Pilot Randomized Crossover Feasibility Trial With Preliminary Inflammatory and Metabolic Outcomes

TypeinterventionalSponsorTzu Chi UniversityRan2023 to 2023Enrolled30ConditionsHealthy, Dietary HabitsArmsPlant-Based Diet, General Diet
3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 2 syntheses or guidelines pooled it, 203 citations in OpenAlex.

  1. Pooled it
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  6. Role of HMGB1 in Neuroinflammation.Molecular neurobiology · 2026
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hanbing DongDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
Yue ZhangDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
Yu HuangDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
Hui DengDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
First Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand pattern recognition receptor capable of binding to a range of structurally diverse ligands, expressed on a variety of cell types, and performing different functions. The ligand-RAGE axis can trigger a range of signaling events that are associated with diabetes and its complications, neurological disorders, cancer, inflammation and other diseases. Since RAGE is involved in the pathophysiological processes of many diseases, targeting RAGE may be an effective strategy to block RAGE signaling.

Indexed as

InflammationReceptor for Advanced Glycation End ProductsDiabetes MellitusHumansLigandsSignal TransductionLigandsReceptor for Advanced Glycation End Productsinflammatory diseasesligandsRAGERAGE inhibitorssignaling

Identifiers

PMID35967420
PMCPMC9373849
OpenAlexW4288693269

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.