Evidence map›Paper›PMID 35967345›Full record

ArticleFrontiers in immunology2022

microRNA-144/451 decreases dendritic cell bioactivity

Zhijie Lin, Xiaoyan Xie, Min Gu, Qian Chen, Guotao Lu, Xiaoqin Jia, Weiming Xiao, Jun Zhang, Duonan Yu, Weijuan Gong

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Lipid metabolism in homeostasis and disease.Signal transduction and targeted therapy · 2026
    Review
  3. Article
  4. Review
  5. miR-144/451: A Regulatory Role in Inflammation.Current molecular medicine · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. miRNA Molecules-Late Breaking Treatment for Inflammatory Bowel Diseases?International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zhijie LinDepartment of Immunology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Xiaoyan XieDepartment of Immunology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Min GuDepartment of Immunology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Qian ChenDepartment of Immunology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Guotao LuDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.
Xiaoqin JiaJiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou University, Yangzhou, China.
Weiming XiaoDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.
Jun ZhangDepartment of Blood Transfusion, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.
Duonan YuJiangsu Key Laboratory of Experimental & Translational Non-coding RNA Research, Yangzhou University, Yangzhou, China.
Weijuan GongDepartment of Immunology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microRNAs miR-144/451 are highly conserved miRNA that is strongly induced during erythropoiesis. Despite the biological functions of miR-144/451 have been extensively studied in erythropoiesis and tumorigenesis, few studies have been conducted in immune responses. In this study, we showed that miR-144/451

Indexed as

ColitisDendritic CellsInflammatory Bowel DiseasesInterferon Regulatory FactorsMicroRNAsAnimalsDisease Models, AnimalFactor VHumansInterferonsLeukocytes, MononuclearMiceFactor VInterferon Regulatory FactorsInterferonsIRF5 protein, humanIrf5 protein, mouseMicroRNAsMIRN144 microRNA, humanMIRN144 microRNA, mouseMIRN451 microRNA, humanMirn451 microRNA, mousedendritic cellimmune regulationinflammatory bowel diseaseinterferon-regulatory factor 5miR-144/451

Identifiers

PMID35967345
PMCPMC9372465
OpenAlexW4288489038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.