Evidence map›Paper›PMID 35967338›Full record

ArticleFrontiers in immunology2022

Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.

Georgia Papapavlou Lingehed, Sandra Hellberg, Jesse Huang, Mohsen Khademi, Ingrid Kockum, Hanna Carlsson, Ivar Tjernberg, Maria Svenvik, Jonas Lind, Marie Blomberg and 6 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Prominent epigenetic and transcriptomic changes in CD4Journal of neuroinflammation · 2023
    Article
  6. CCL13 and human diseases.Frontiers in immunology · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Georgia Papapavlou LingehedDivision of Inflammation and Infection, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Sandra HellbergDivision of Bioinformatics, Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden.
Jesse HuangNeuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.
Mohsen KhademiNeuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.
Ingrid KockumNeuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.
Hanna CarlssonDepartment of Clinical Chemistry and Transfusion Medicine, Region Kalmar County, and Department of Biomedical and Clinical Sciences, Division of Inflammation and Infection, Linköping University, Linköping, Sweden.
Ivar TjernbergDepartment of Clinical Chemistry and Transfusion Medicine, Region Kalmar County, and Department of Biomedical and Clinical Sciences, Division of Inflammation and Infection, Linköping University, Linköping, Sweden.
Maria SvenvikDepartment of Obstetrics and Gynecology, Region Kalmar County, Kalmar, Sweden and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Jonas LindSection of Neurology, Department of Internal Medicine, County Hospital Ryhov, Jönköping, Sweden and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Marie BlombergDepartment of Obstetrics and Gynecology in Linköping, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Magnus VrethemDepartment of Neurology, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Johan MellergårdDepartment of Neurology, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Mika GustafssonDivision of Bioinformatics, Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden.
Maria C JenmalmDivision of Inflammation and Infection, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Tomas OlssonNeuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.
Jan ErnerudhDepartment of Clinical Immunology and Transfusion Medicine, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Linköping University · SEKarolinska Institutet · SEKarolinska University Hospital · SERyhov Hospital Jönköping · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is a chronic autoimmune neuroinflammatory and neurodegenerative disorder of the central nervous system. Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3

Indexed as

Multiple SclerosisPregnancy ComplicationsBlood ProteinsFemaleHumansImmunomodulationPregnancyPregnancy TrimestersBlood Proteinscytokineshormonesinflammationmultiple sclerosisOlink proteomicsplasmapregnancy

Identifiers

PMID35967338
PMCPMC9373039
OpenAlexW4288535575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.