Evidence map›Paper›PMID 35967334›Full record

SynthesisFrontiers in immunology2022

Effects of tobacco smoking on cardiovascular disease in patients with systemic lupus erythematosus: A systematic review and meta-analysis.

Wan-Tong Zhang, Zhao Liu, Bao-Chen Zhu, Zi-Yang Cui, Cheng Huang, Xu-Jie Wang, Fang Lu, Qiu-Yan Li, Wei-Liang Weng, Guo-Dong Hua and 1 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Wan-Tong ZhangInstitute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Zhao LiuDepartment of Tobacco Control and Prevention of Respiratory Disease, China-Japan Friendship Hospital, Beijing, China.
Bao-Chen ZhuDepartment of Pharmacy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Zi-Yang CuiDepartment of Geriatric Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Cheng HuangDepartment of Orthopaedics, China-Japan Friendship Hospital, Beijing, China.
Xu-Jie WangInstitute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Fang LuInstitute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Qiu-Yan LiNational Medical Products Administration (NMPA) Key Laboratory for Clinical Research and Evaluation of Traditional Chinese Medicine, Beijing, China.
Wei-Liang WengInstitute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Guo-Dong HuaDepartment of Pharmacy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Chun-Miao XueDepartment of Pharmacy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
National Medical Products Administration · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNChina-Japan Friendship Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with systemic lupus erythematosus (SLE) are at increased risk of cardiovascular disease (CVD) compared to the general population. However, little is known about the effects of tobacco smoking on CVD in patients with SLE. Objective: To systematically review and summarize the available literature regarding the effects of tobacco smoking on developing CVD in patients with SLE. Methods: We retrieved relevant studies from the following databases: PubMed, EMBASE, Web of Science and China National Knowledge Internet (CNKI) database. Two reviewers independently reviewed the eligible studies, assessed their validity, and extracted relevant data. Sensitivity and subgroup analyses were performed to distinguish sources of heterogeneity. Results: A total of 10 studies, which comprised 6984 participants, were included in the analysis. The overall quality of evidence was rated as moderate to low. The smoking prevalence among CVD patients was 39.28% (271/690), which was higher than 31.36% (1974/6294) among non-CVD patients. Compared with never-smokers, the risk of developing CVD in current smokers was 1.42 (95% CI: 1.21-1.66). No significant publication bias was found in our meta-analysis. Conclusions: In spite of the several negative results, this study found that current smokers with SLE have an increased risk of developing CVD, although most of the included studies were in low-to-moderate quality. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42022338109.

Indexed as

Cardiovascular DiseasesLupus Erythematosus, SystemicHumansPrevalenceSmokingTobacco Smokingcardiovascular diseasemeta-analysissystematic reviewsystemic lupus erythematosustobacco smoking

Identifiers

PMID35967334
PMCPMC9364766
OpenAlexW4288068272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.