ArticleJTCVS techniques2022
Quantitative biomechanical optimization of neochordal implantation location on mitral leaflets during valve repair.
Article in JTCVS techniques, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Design and evaluation of valve interventions using ex vivo biomechanical modeling: the Stanford experience.General thoracic and cardiovascular surgery · 2025Review
- Early and long-term outcomes following redo mitral valve surgery in patients with prior minimally invasive mitral valve surgery.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Biomechanical engineering analysis of neochordae length's impact on chordal forces in mitral repair.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024Article
- Neochords: How long, how many, too many?JTCVS techniques · 2023Article
- Chordal force profile after neochordal repair of anterior mitral valve prolapse: An ex vivo study.JTCVS open · 2023Article
- Utilization of Engineering Advances for Detailed Biomechanical Characterization of the Mitral-Ventricular Relationship to Optimize Repair Strategies: A Comprehensive Review.Bioengineering (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 2 countries.
Funding
Abstract
Objective: Suture pull-out remains a significant mechanism of long-term neochordal repair failure, as demonstrated by clinical reports on recurrent mitral valve regurgitation and need for reoperation. The objective of this study was to provide a quantitative comparison of suture pull-out forces for various neochordal implantation locations. Methods: Posterior leaflets were excised from fresh porcine mitral valves (n = 54) and fixed between two 3-dimensional-printed plates. Gore-Tex CV-5 sutures (WL Gore & Associates Inc) were placed with distances from the leading edge and widths between anchoring sutures with values of 2 mm, 6 mm, and 10 mm for a total of 9 groups (n = 6 per group). Mechanical testing was performed using a tensile testing machine to evaluate pull-out force of the suture through the mitral valve leaflet. Results: Increasing the suture anchoring width improved failure strength significantly across all leading-edge distances ( Conclusions: Increasing suture anchoring width and leading-edge distance improves the suture pull-out force through the mitral leaflet, which may optimize postrepair durability. The results suggest a comparative advantage to increasing suture anchoring width compared with leading-edge distance.
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Registered trials
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