Evidence map›Paper›PMID 35967038›Full record

ArticleACS omega2022

Hydrochloride Salt of the GABAkine KRM-II-81.

Md Yeunus Mian, Branka Divović, Dishary Sharmin, Kamal P Pandey, Lalit K Golani, V V N Phani Babu Tiruveedhula, Rok Cerne, Jodi L Smith, Xingjie Ping, Xiaoming Jin and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Md Yeunus MianDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States.ORCID https://orcid.org/0000-0002-7520-1750
Branka DivovićDepartment of Pharmacology, Faculty of Pharmacy, University of Belgrade, Belgrade 11000, Serbia.
Dishary SharminDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States.
Kamal P PandeyDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States.ORCID https://orcid.org/0000-0002-0723-2264
Lalit K GolaniDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States.
V V N Phani Babu TiruveedhulaDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States.
Rok CerneLaboratory of Antiepileptic Drug Discovery, St. Vincent's Hospital, Indianapolis, Indiana 46260, United States.
Jodi L SmithLaboratory of Antiepileptic Drug Discovery, St. Vincent's Hospital, Indianapolis, Indiana 46260, United States.
Xingjie PingDepartment of Anatomy and Cell Biology, Indiana University/Purdue University, Indianapolis, Indiana 46202, United States.
Xiaoming JinDepartment of Anatomy and Cell Biology, Indiana University/Purdue University, Indianapolis, Indiana 46202, United States.
Gregory H ImlerNaval Research Laboratory, Washington, District of Columbia 20375, United States.ORCID https://orcid.org/0000-0002-9686-9186
Jeffrey R DeschampsNaval Research Laboratory, Washington, District of Columbia 20375, United States.
Arnold LippaRespireRx Pharmaceuticals Inc., Glen Rock, New Jersey 07452, United States.
James M CookDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States.ORCID https://orcid.org/0000-0001-5512-3022
Miroslav M SavićDepartment of Pharmacology, Faculty of Pharmacy, University of Belgrade, Belgrade 11000, Serbia.ORCID https://orcid.org/0000-0002-6934-9193
James RowlettDepartment of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, Mississippi 39216, United States.
Jeffrey M WitkinDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States.
University of Wisconsin–Milwaukee · USSt. Vincent's Birmingham · USIndiana University – Purdue University Indianapolis · USUnited States Naval Research Laboratory · USUniversity of Belgrade · RSUniversity of Mississippi Medical Center · US

Funding

ANXIOLYTIC EFFECTS AND ABUSE OF BZ RECEPTOR LIGANDSR01DA011792 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI ROWLETT, JAMES K · 1998 to 2024
$7.8M
Tolerance and Physical Dependence after Chronic Benzodiazepine TreatmentR01DA043204 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI JAMES K ROWLETT · 2017 to 2026
$4.3M
Synthesis of Alpha2/Alpha3 GABA Agonists to Treat Neuropathic PainR01NS076517 · NINDS · UNIVERSITY OF WISCONSIN MILWAUKEE · PI COOK, JAMES M · 2012 to 2015
$1.3M
NIDA NIH HHS R01 DA011792NIDA NIH HHS R01 DA043204NINDS NIH HHS R01 NS076517
6 · The paper itself

Abstract

Imidazodiazepine (5-(8-ethynyl-6-(pyridin-2-yl)-4

Identifiers

PMID35967038
PMCPMC9366947
OpenAlexW4288051415

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.