ArticleFrontiers in human neuroscience2022
Cerebellar and brainstem differences in children with developmental coordination disorder: A voxel-based morphometry study.
Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Sensory processing and neurodevelopmental disorder traits in 4- to 5-year-old Dutch children adjusted for sex, neurodevelopment in infancy and IQ.European child & adolescent psychiatry · 2026Article
- Associations between neonatal brain structure and neurodevelopmental outcomes following very preterm birth.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Motor intervention therapy for children with developmental coordination disorder: from behavioral improvement to neuroplasticity mechanisms.Frontiers in human neuroscience · 2026Review
- Sensory processing in Brazilian children with developmental coordination disorder, possible DCD, and typical development: a case-control study.European child & adolescent psychiatry · 2025Article
- Regional gray matter volume is associated with motor imagery performance in children with and without developmental coordination disorder.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- The sensory profile of students with probable developmental coordination disorder (DCD).Scientific reports · 2025Article
- Exploring the Association Between Cerebellar Regional Volumes and Health-Related Quality of Life in Patients with Ischemic Stroke: A Prospective Cohort Study.Cerebellum (London, England) · 2025Article
- Investigating Motor Coordination Using BXD Recombinant Inbred Mice to Model the Genetic Underpinnings of Developmental Coordination Disorder.Genes, brain, and behavior · 2025Article
- Motor Signature Differences Between Autism Spectrum Disorder and Developmental Coordination Disorder, and Their Neural Mechanisms.Journal of autism and developmental disorders · 2025Article
- Can attention-deficit/hyperactivity disorder be considered a form of cerebellar dysfunction?Frontiers in neuroscience · 2025Article
- Anticipatory postural adjustment deficits in children with developmental coordination disorder during a self-induced prehension task while standing on one leg.Scientific reports · 2024Article
- Interlimb Coordination and Auditory-Motor Synchronization in Children with Developmental Coordination Disorder: Examining Antiphase Knee Movements with Auditory Metronomes While Seated.Children (Basel, Switzerland) · 2024Article
- Cerebellum in Alzheimer's disease and other neurodegenerative diseases: an emerging research frontier.MedComm · 2024Review
- Motor competence is related to acquisition of error-based but not reinforcement learning in children ages 6 to 12.Heliyon · 2024Article
- Motor Adaptation Deficits in Children with Developmental Coordination Disorder and/or Reading Disorder.Children (Basel, Switzerland) · 2024Article
- Cortical grey matter volume differences in children with developmental coordination disorder compared to typically developing children.Frontiers in human neuroscience · 2024Article
- Developmental coordination disorder: What can we learn from RI mice using motor learning tasks and QTL analysis.Genes, brain, and behavior · 2023Article
- Cerebellar Differences after Rehabilitation in Children with Developmental Coordination Disorder.Brain sciences · 2022Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Developmental coordination disorder (DCD) is a neurodevelopmental disorder that significantly impairs a child's ability to learn motor skills and to perform everyday activities. The cause of DCD is unknown; however, evidence suggests that children with DCD have altered brain structure and function. While the cerebellum has been hypothesised to be involved in developmental coordination disorder, no studies have specifically examined cerebellar structure in this population. The purpose of our study was to examine cerebellar differences in children with DCD compared to typically-developing children. Using voxel-based morphometry, we assessed cerebellar morphology in children 8-12 years of age. Forty-six children (12 typically-developing and 34 with DCD) were investigated using high resolution T1-weighted images, which were then processed using the spatially unbiased atlas template of the cerebellum and brainstem (SUIT) toolbox for a region of interest-based examination of the cerebellum. Results revealed that children with DCD had reduced grey matter volume in several regions, namely: the brainstem, right/left crus I, right crus II, left VI, right VIIb, and right VIIIa lobules. Further, Pearson correlations revealed significant positive associations between the total motor percentile score on the Movement Assessment Battery for Children-2 and regions that had reduced grey matter volume in our cohort (brainstem, left crus I, right VIIb, and right VIIIa). These findings indicate that reductions in cerebellar grey matter volume are associated with poorer motor skills. Given the cerebellum's involvement in internal models of movement, results of this study may help to explain why children with DCD struggle to learn motor skills.
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