Evidence map›Paper›PMID 35966866›Full record

ArticleFrontiers in medicine2022

Robert J Schillinger, Simutanyi Mwakamui, Chola Mulenga, Mizinga Tembo, Phoebe Hodges, Ellen Besa, Kanta Chandwe, Victor O Owino, Christine A Edwards, Paul Kelly and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Associations ofCurrent developments in nutrition · 2025
    Article
  3. A cross-sectional study of associations between theThe American journal of clinical nutrition · 2024
    Observational
  4. Article
  5. A Model-BasedThe Journal of nutrition · 2024
    Article
  6. Article
  7. Mechanistic inference of the metabolic rates underlyingJournal of pharmacokinetics and pharmacodynamics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Robert J SchillingerScottish Universities Environmental Research Centre, University of Glasgow, East Kilbride, United Kingdom.
Simutanyi MwakamuiTropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.
Chola MulengaTropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.
Mizinga TemboTropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.
Phoebe HodgesTropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.
Ellen BesaTropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.
Kanta ChandweTropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.
Victor O OwinoNutritional and Health-Related Environmental Studies Section, Division of Human Health, International Atomic Energy Agency (IAEA), Vienna, Austria.
Christine A EdwardsSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, United Kingdom.
Paul KellyTropical Gastroenterology and Nutrition Group, University of Zambia School of Medicine, Lusaka, Zambia.
Douglas J MorrisonScottish Universities Environmental Research Centre, University of Glasgow, East Kilbride, United Kingdom.
Tropical Gastroenterology & Nutrition group · ZMUniversity of Glasgow · GBInternational Atomic Energy Agency · ATQueen Mary University of London · GBUniversity of Zambia · ZM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Environmental enteropathy (EE) is a subclinical disorder highly prevalent in tropical and disadvantaged populations and is thought to play a role in growth faltering in children, poor responses to oral vaccines, and micronutrient deficiencies. This study aims to evaluate the potential of a non-invasive breath test based on stable isotopes for evaluation of impaired digestion and absorption of sucrose in EE. Methods: We optimized a Results: Fully labeled sucrose (0.3 mg/kg) provided clear breath enrichment signals over 2-3 h in both British and Zambian adults, more than fivefold higher than naturally enriched sucrose. Reducose dramatically impaired Conclusion: A

Indexed as

13C-breath testenvironmental enteropathygut functionintestinal sucrase activitymalnutritionstunting

Identifiers

PMID35966866
PMCPMC9372340
OpenAlexW4288423773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.