Evidence map›Paper›PMID 35966793›Full record

ArticleFrontiers in aging neuroscience2022

A novel curcumin oil solution can better alleviate the motor activity defects and neuropathological damage of a Parkinson's disease mouse model.

Xiwen Geng, Hao Zhang, Minghui Hu, Xiaoyu Liu, Min Han, Jinlu Xie, Zifa Li, Feng Zhao, Wei Liu, Sheng Wei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Lead Phytomolecules for Treating Parkinson's Disease.Central nervous system agents in medicinal chemistry · 2025
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Xiwen GengExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, China.
Hao ZhangExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, China.
Minghui HuExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, China.
Xiaoyu LiuInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Min HanInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Jinlu XieKey Laboratory of Vector Biology and Pathogen Control of Zhejiang, School of Medicine, Huzhou Central Hospital, Huzhou University, Huzhou, China.
Zifa LiExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, China.
Feng ZhaoExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, China.
Wei LiuDepartment of Encephalopathy, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Sheng WeiExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, China.
Shandong University of Traditional Chinese Medicine · CNAffiliated Hospital of Shandong University of Traditional Chinese Medicine · CNHuzhou University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin has been reported to improve or prevent movement disorders in Parkinson's disease (PD); however, its low bioavailability is the biggest obstacle to its application. To optimize the limited efficacy of curcumin and to improve its protective effects against PD, we prepared and tested a novel curcumin oil solution.

Indexed as

bioavailabilitycurcumindopaminergic neuronParkinson’s diseaseprotective effect

Identifiers

PMID35966793
PMCPMC9372469
OpenAlexW4288489050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.