Evidence map›Paper›PMID 35966739›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Ultrasound Comparative Analysis of Coronary Arteries before and after Immune Blocking Therapy with Gamma Globulin in Children with Kawasaki Disease.

Yi Yu, Jinhua Hu, Qun Xia, Juxia Huang, Yangmei Cheng, Fangling Wu, Yujing Liu, Jun Wang, Qiong Zhang

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yi YuDepartment of Ultrasound, Anqing First People's Hospital Affiliated to Anhui Medical University, Anqing, Anhui, China.
Jinhua HuDepartment of Ultrasound, Anqing First People's Hospital Affiliated to Anhui Medical University, Anqing, Anhui, China.
Qun XiaDepartment of Ultrasound, Anqing First People's Hospital Affiliated to Anhui Medical University, Anqing, Anhui, China.
Juxia HuangDepartment of Ultrasound, Anqing First People's Hospital Affiliated to Anhui Medical University, Anqing, Anhui, China.
Yangmei ChengDepartment of Ultrasound, Anqing First People's Hospital Affiliated to Anhui Medical University, Anqing, Anhui, China.
Fangling WuDepartment of Ultrasound, Anqing First People's Hospital Affiliated to Anhui Medical University, Anqing, Anhui, China.
Yujing LiuDepartment of Ultrasound, Anqing First People's Hospital Affiliated to Anhui Medical University, Anqing, Anhui, China.
Jun WangDepartment of Ultrasound, Anqing First People's Hospital Affiliated to Anhui Medical University, Anqing, Anhui, China.
Qiong ZhangDepartment of Child Health, Shiyan Maternal and Child Health Hospital, Shiyan, Hubei, China.ORCID https://orcid.org/0000-0001-9866-4873
Anhui Medical University · CNPeople's Hospital of Shiyan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the ultrasound characteristics and clinical efficacy of coronary arteries before and after immune blocking therapy with gamma globulin in children with Kawasaki disease. Methods: A total of 64 children with Kawasaki disease who were treated in our hospital from January 2018 to October 2021 were selected. All the children were given immune blocking therapy with gamma globulin on the basis of conventional treatment. The disappearance time of related symptoms and signs (fever, mucosal congestion, cervical lymphadenopathy, and swelling of the hands and feet) in children were counted. The white blood cell count (WBC), platelet count (PLT), C-reactive protein (CRP), and procalcitonin (PCT) levels of the children before and after treatment were compared, and the characteristics of coronary echocardiography before and after treatment were observed for analysis and discussion, to carefully observe whether the coronary artery involvement of the children was improved. Results: The inner diameter of the left and right coronary arteries significantly decreased ( Conclusion: The effect of gamma globulin in the treatment of Kawasaki disease is remarkable, which can improve the blood indexes, VEGF, and endostatin levels in children, significantly reduce coronary dilatation, and reduce the incidence of coronary artery disease. Echocardiography is of high value in the examination of children with Kawasaki disease, which can accurately detect the size, location, and inner diameter of coronary artery lesions, and can effectively evaluate the treatment effect on children.

Identifiers

PMID35966739
PMCPMC9371854
OpenAlexW4290085624

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.