ArticleFrontiers in microbiology2022
Shotgun metagenomic sequencing reveals skin microbial variability from different facial sites.
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Precise assessment of facial skin based on multimodal data fusion of the microbiome.Quantitative biology (Beijing, China) · 2026Article
- The Bacterial Landscape of Facial Skin: From Homeostasis to Skin Conditions.Dermatology and therapy · 2026Review
- Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age-related processes leading to Porphyr'ageing.International journal of cosmetic science · 2026Article
- Spatial and temporal patterns of public transit aerobiomes.Microbiome · 2026Article
- From acidification to multi-targeted cellular modulation: dual impact of hydroxy acids on the skin microbiota and the epidermal barrier.Frontiers in cellular and infection microbiology · 2026Review
- Rebalancing the Skin: The Microbiome, Acne Pathogenesis, and the Future of Natural and Synthetic Therapies.Molecules (Basel, Switzerland) · 2025Review
- Wounds and the Microbiota: The Healing Interplay Between Host and Microbial Communities.International journal of molecular sciences · 2025Review
- A comprehensive reference catalog of human skin DNA virome reveals novel viral diversity and microenvironmental influences.Microbiology spectrum · 2025Article
- Review
- The microbiome of the human facial skin is unique compared to that of other hominids.mSystems · 2025Article
- Culture dependent and independent approaches reveal the role of specific bacteria in human skin aging.iMetaOmics · 2024Article
- The Role of the Skin Microbiome in Acne: Challenges and Future Therapeutic Opportunities.International journal of molecular sciences · 2024Review
- Chronic exposure to polycyclic aromatic hydrocarbons alters skin virome composition and virus-host interactions.The ISME journal · 2024Article
- Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa.Current drug targets · 2024Review
- Metagenomics: An Effective Approach for Exploring Microbial Diversity and Functions.Foods (Basel, Switzerland) · 2023Review
- The Skin Microbiome: Current Techniques, Challenges, and Future Directions.Microorganisms · 2023Review
- Detection of antimicrobial producingFrontiers in microbiology · 2023Article
- Evolving approaches to profiling the microbiome in skin disease.Frontiers in immunology · 2023Review
- Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem.Phenomics (Cham, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biogeography (body site) is known to be one of the main factors influencing the composition of the skin microbial community. However, site-associated microbial variability at a fine-scale level was not well-characterized since there was a lack of high-resolution recognition of facial microbiota across kingdoms by shotgun metagenomic sequencing. To investigate the explicit microbial variance in the human face, 822 shotgun metagenomic sequencing data from Han Chinese recently published by our group, in combination with 97 North American samples from NIH Human Microbiome Project (HMP), were reassessed. Metagenomic profiling of bacteria, fungi, and bacteriophages, as well as enriched function modules from three facial sites (forehead, cheek, and the back of the nose), was analyzed. The results revealed that skin microbial features were more alike in the forehead and cheek while varied from the back of the nose in terms of taxonomy and functionality. Analysis based on biogeographic theories suggested that neutral drift with niche selection from the host could possibly give rise to the variations. Of note, the abundance of porphyrin-producing species, i.e.,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.