Evidence map›Paper›PMID 35966593›Full record

ArticleTheranostics2022

MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKKβ and inducing IKKβ-mediated FoxO1 nuclear export and Foxp3 downregulation.

Jyun-Ni Chi, Jhih-Yu Yang, Chia-Hsin Hsueh, Ching-Yi Tsai, Huai-Chia Chuang, Tse-Hua Tan

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Abnormal Elevation of the Expression of Costimulatory Molecule CD226 in Graves' DiseaseEndocrine, metabolic & immune disorders drug targets · 2026
    Article
  4. Review
  5. Differentiation and regulation of CD4Cellular and molecular life sciences : CMLS · 2024
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jyun-Ni ChiImmunology Research Center, National Health Research Institutes, Zhunan, Taiwan.
Jhih-Yu YangImmunology Research Center, National Health Research Institutes, Zhunan, Taiwan.
Chia-Hsin HsuehImmunology Research Center, National Health Research Institutes, Zhunan, Taiwan.
Ching-Yi TsaiImmunology Research Center, National Health Research Institutes, Zhunan, Taiwan.
Huai-Chia ChuangImmunology Research Center, National Health Research Institutes, Zhunan, Taiwan.
Tse-Hua TanImmunology Research Center, National Health Research Institutes, Zhunan, Taiwan.
National Health Research Institutes · TWBaylor College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Autoimmune DiseasesI-kappa B KinaseActive Transport, Cell NucleusAnimalsDown-RegulationForkhead Box Protein O1Forkhead Transcription FactorsMiceProtein Kinase C-thetaProtein KinasesProtein Serine-Threonine KinasesRNA, MessengerT-Lymphocytes, RegulatoryTranscription FactorsForkhead Box Protein O1Forkhead Transcription FactorsFoxo1 protein, mouseFoxp3 protein, mouseGCK-like kinaseI-kappa B KinaseProtein Kinase C-thetaProtein KinasesProtein Serine-Threonine KinasesRNA, MessengerTranscription FactorsFoxO1Foxp3IKKβMAP4K3/GLKTreg

Identifiers

PMID35966593
PMCPMC9373822
OpenAlexW4285819385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.