Evidence map›Paper›PMID 35966546›Full record

ArticleFrontiers in cardiovascular medicine2022

Graft preservation confers myocardial protection during coronary artery bypass grafting.

Philipp Szalkiewicz, Maximilian Y Emmert, Paul P Heinisch, Zsuzsanna Arnold, Ingo Crailsheim, Markus Mach, Thomas Aschacher, Martin Grabenwöger, Bernhard Winkler

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Philipp SzalkiewiczKarl Landsteiner Institute for Cardiac and Vascular Surgical Research, Vienna, Austria.
Maximilian Y EmmertDeutsches Herzzentrum Berlin, Berlin, Germany.
Paul P HeinischGerman Heart Centre Munich, Technical University Munich, Munich, Germany.
Zsuzsanna ArnoldKarl Landsteiner Institute for Cardiac and Vascular Surgical Research, Vienna, Austria.
Ingo CrailsheimKarl Landsteiner Institute for Cardiac and Vascular Surgical Research, Vienna, Austria.
Markus MachMedical University of Vienna, Vienna, Austria.
Thomas AschacherKarl Landsteiner Institute for Cardiac and Vascular Surgical Research, Vienna, Austria.
Martin GrabenwögerKarl Landsteiner Institute for Cardiac and Vascular Surgical Research, Vienna, Austria.
Bernhard WinklerKarl Landsteiner Institute for Cardiac and Vascular Surgical Research, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: During on-pump coronary artery bypass grafting (ONCAB), graft flushing for distal anastomoses testing also perfuses the downstream myocardium. This single-center retrospective study evaluated the impact of specific preservation solutions on myocardial protection during ONCAB. Materials and methods: Between July 2019 and March 2020 either DuraGraft (DG) or 0.9% Saline/Biseko (SB) was applied to 272 ONCAB. Overall, 166 patients were propensity-matched into two groups. Cardiac enzymes [high-sensitive Troponin I (hs-TnI) and creatine kinase (CK)] were evaluated 7 days post-surgery. Results: Post-surgery, hs-TnI values were significantly lower from 3 to 6 h (h) up to 4 days in the DG group: 3-6 h: 4,034 ng/L [IQR 1,853-8,654] vs. 5,532 ng/L [IQR 3,633-8,862], Conclusion: Repeated graft flushing with DG resulted in lower Troponin values post-surgery suggesting enhanced myocardial protection compared to SB. Additional studies are warranted to further assess the myocardial protection properties of DG.

Indexed as

coronary arterymyocardiumprotectionstorage solutionsvein graft preservation

Identifiers

PMID35966546
PMCPMC9365949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.