Evidence map›Paper›PMID 35966526›Full record

ArticleFrontiers in cardiovascular medicine2022

Epidemiology of atrial fibrillation and risk of CVD mortality among hypertensive population: A prospective cohort study in Northeast China.

Zhi Du, Min Lin, Yuanmeng Tian, Li Jing, Shuang Liu, Guangxiao Li, Tong Jia, Qun Sun, Lei Shi, Jixu Sun and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Zhi DuDepartment of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Min LinDepartment of Cardiovascular Medicine, Benxi Central Hospital, Benxi, China.
Yuanmeng TianInstitute of Preventive Medicine, China Medical University, Shenyang, China.
Li JingInstitute of Preventive Medicine, China Medical University, Shenyang, China.
Shuang LiuDepartment of Ultrasound, The Fourth Hospital of China Medical University, Shenyang, China.
Guangxiao LiDepartment of Medical Record Management Center, The First Affiliated Hospital of China Medical University, Shenyang, China.
Tong JiaCollege of Information Science and Engineering, Northeastern University, Shenyang, China.
Qun SunDepartment of Chronic Disease, Disease Control and Prevention of Chaoyang City, Chaoyang, China.
Lei ShiDepartment of Chronic Disease, Disease Control and Prevention of Liaoyang City, Liaoyang, China.
Jixu SunDepartment of Chronic Disease, Disease Control and Prevention of Dandong City, Dandong, China.
Wen TianDepartment of Geriatric Cardiology, The First Affiliated Hospital of China Medical University, Shenyang, China.
Liying XingInstitute of Preventive Medicine, China Medical University, Shenyang, China.
China Medical University · CNBeijing Chaoyang Emergency Medical Center · CNFirst Affiliated Hospital Zhejiang University · CNNortheastern University · CNXian Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Determining risk factors of cardiovascular disease (CVD)-related mortality and evaluating their influence are important for effectively reducing corresponding mortality. However, few research findings have estimated the relationship between atrial fibrillation (AF) and CVD-related mortality among hypertension individuals. Objective: The objective of this study was to investigate the epidemiology of AF in a hypertension population and determine the relationship between AF and CVD-related mortality. Methods: Using a multistage, stratified, and cluster random sampling method, the prospective cohort study with a median follow-up of 3.51 years enrolled 10,678 hypertensive participants at baseline. The prevalence, awareness, and anticoagulation data of AF in this focal population were carefully assessed. Stepwise logistic regression and Cox regression analysis were respectively performed to evaluate the determinants of AF and the association between AF and CVD-related mortality. Results: The overall prevalence of AF was 1.3% (95% CI, 1.1%-1.6%) in the hypertensive population, and it was higher in men than in women (1.8% vs. 1.0%, respectively; p=0.001). The awareness of AF was 53.1%, and the rate of oral anticoagulant (OAC) therapy was only 4.2%, although all AF participants should have required according to the European Society of Cardiology guidelines. The determinants of AF included elder, male, and history of coronary heart disease in the hypertensive population. Besides, compared with individuals without AF, the risk of CVD-related mortality significantly increased in the hypertensive population with AF (HR 3.37, 95% CI 2.10-5.40). Conclusion: Our results indicated a huge burden of AF and underuse of OAC therapy for them in a community-based hypertensive population. Considering that most of the risk factors of AF were unmodifiable in hypertensive individuals, as well as its high risk of mortality, long-term interventions including AF education, timely screening, and widespread use of OACs should be emphasized in the focal populations.

Indexed as

atrial fibrillationCVD mortalityepidemiologyoral anticoagulant therapyrisk factor

Identifiers

PMID35966526
PMCPMC9366344
OpenAlexW4288080634

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.