Evidence map›Paper›PMID 35966185›Full record

ArticleInternational journal of surgery case reports2022

Life-threatening gastrointestinal haemorrhage requiring surgical resection caused by SARS-CoV-2 induced ANCA associated vasculitis: A case report.

Thomas Giles, Susmit Prosun Roy, Dani Chandrasoma, Stephen Oakley, Kyaw Lynnhtun, Brian Draganic

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Thomas GilesDepartment of General Surgery, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia.
Susmit Prosun RoyDepartment of General Surgery, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia. Electronic address: susmit.roy@health.NSW.gov.au.
Dani ChandrasomaDepartment of Rheumatology, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia.
Stephen OakleyDepartment of Rheumatology, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia; School of Medicine and Public Health, University of Newcastle, NSW, Australia.
Kyaw LynnhtunDepartment of Pathology, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia; School of Medicine and Public Health, University of Newcastle, NSW, Australia.
Brian DraganicDepartment of General Surgery, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia.
John Hunter Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and importance: SARS-CoV-2 infection has been linked to the Case presentation: A 28-year-old male presented to our tertiary referral centre with progressive debilitating polyarthritis, a purpuric rash on both flanks and aphthous ulcers 6 weeks after infection with SARS-CoV-2. On the second day of admission, he developed severe gastrointestinal haemorrhage requiring multiple blood transfusions. Attempted angioembolisation failed to identify a site of active haemorrhage. On failing trial of conservative management, the decision was made to perform an exploratory laparotomy. The small bowel was found to have an extensive vasculitis requiring resection to control haemorrhage. Autoimmune serology revealed c-ANCA positivity with anti-PR3 antibodies. Clinical discussion: Patients presenting with acute vasculitic pathologies related to SARS-CoV-2 have the potential to rapidly progress to severe life-threatening gastrointestinal haemorrhage. Prompt surgical management is appropriate in selected cases. Conclusion: In the current era of COVID-19, the differential diagnosis of SARS-CoV-2 induced ANCA vasculitis must be considered for such cases with gastrointestinal haemorrhage. Compilation of similar cases and further studies are required to determine an optimal management pathway for these patients.

Indexed as

Case reportCOVID-19Gastrointestinal haemorrhageGastrointestinal vasculitisSARS-CoV-2 associated vasculitis

Identifiers

PMID35966185
PMCPMC9361579
OpenAlexW4290786210

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.