Evidence map›Paper›PMID 35966156›Full record

ArticleAsia Pacific allergy2022

Prevalence of IgE-mediated cow milk, egg, and peanut allergy in young Singapore children.

Alison Joanne Lee, Elizabeth Huiwen Tham, Anne Eng-Neo Goh, Wern-Ee Tang, Yew-Cheong Tung, Yehudi Yeo, Keith Tsou, Le-Ye Lee, Jian-Yi Soh, Cesar Brence Labastida and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Asia Pacific allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Exploring geographical variances in component-resolved diagnosis within the Asia-Pacific region.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  6. Review
  7. APAAACI's activities and this issue.Asia Pacific allergy · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Alison Joanne LeeKhoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.ORCID 0000-0001-8623-6724
Elizabeth Huiwen ThamKhoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.ORCID 0000-0003-1037-6143
Anne Eng-Neo GohDepartment of Paediatrics, KKH Women's and Children's Hospital, Singapore.ORCID 0000-0001-5697-0813
Wern-Ee TangNational Healthcare Group of Polyclinics (NHGP), Singapore.ORCID 0000-0003-0019-6747
Yew-Cheong TungNational Healthcare Group of Polyclinics (NHGP), Singapore.ORCID 0000-0002-2886-5028
Yehudi YeoNational Healthcare Group of Polyclinics (NHGP), Singapore.ORCID 0000-0001-7535-9083
Keith TsouNational University Polyclinics, Singapore.ORCID 0000-0001-5140-7343
Le-Ye LeeDepartment of Neonatology, National University Hospital, Singapore.ORCID 0000-0001-7503-4836
Jian-Yi SohKhoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.ORCID 0000-0002-6135-9434
Cesar Brence LabastidaKhoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.ORCID 0000-0002-2106-8405
Ping-Ping WangKhoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.ORCID 0000-0001-8305-2866
Michelle Mei-Ling TanKhoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.
Hsin Yue ChengDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0002-5207-2319
Yiong-Huak ChanBiostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0002-5076-5269
Hugo Van BeverKhoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.ORCID 0000-0002-6308-2045
Lynette Pei-Chi ShekKhoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore.ORCID 0000-0001-9064-8983
Bee-Wah LeeDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0002-3957-3290
Khoo Teck Puat Hospital · SGNational University of Singapore · SGNational University Hospital · SGNational University Health System · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The rising prevalence of food allergy reported in the United States, UK, and Australia may be attributable to the rise in peanut allergy prevalence. The food allergy prevalence in other parts of the world such as Asia is, however, less well documented. Objective: This study aimed to evaluate the prevalence of cow's milk, egg, and peanut allergies in a general population of Singaporean children below 30 months of age. Methods: A total of 4,115 children from the general population who attended well-baby visits between 2011 and 2015 completed standardized questionnaires to elicit a convincing history of food allergy to estimate the population prevalence of food allergies. Results: The prevalence of a convincing history of cow's milk allergy was 0.51% (95% confidence interval [CI], 0.3-0.7), hen's egg allergy 1.43% (95% CI, 1.1-1.8), and peanut allergy 0.27% (95% CI, 0.12-0.42). Of the 15 of 59 children with a convincing history of hen's egg allergy who consented, 12 (80%) had corroborative positive skin prick tests. Conclusion: The prevalence of food allergy, in particular peanut allergy, in children below 2 years of age is lower in this South East Asian population than reported in Western cohorts. Further research should focus on deciphering differential risk factors for food allergy across different geographical locations.

Indexed as

AsiaChildCow’s milkEggFood allergyPeanut

Identifiers

PMID35966156
PMCPMC9353200
OpenAlexW4288072264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.