Evidence map›Paper›PMID 35966118›Full record

ArticleAmerican journal of ophthalmology case reports2022

Case report: Utilization of neutral density filters for densitometry analysis of dense corneal opacities.

Akhil Meka, Cody Moezzi, Daniel Brocks

Open access · goldAbstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Akhil MekaDepartment of Ophthalmology, BostonSight, Needham, MA, USA.
Cody MoezziDepartment of Ophthalmology, BostonSight, Needham, MA, USA.
Daniel BrocksDepartment of Ophthalmology, BostonSight, Needham, MA, USA.
Boston Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This report describes the technique of utilizing a neutral density filter (NDF) during Scheimpflug imaging of a dense corneal opacity in order to increase data acquisition success and improve data reliability for densitometry analysis. Observations: A 49-year-old female with Steven-Johnson Syndrome secondary to sulfonamide use presented for routine follow up evaluation of her customized ocular surface prosthetic device (PD). Her ocular history was significant for mucous membrane grafting and limbal stem cell transplant in both eyes. The ocular surface examination of the left eye was notable for chronic dense neovascularization and scarring of the temporal and inferior cornea which extended into the visual axis. Scheimpflug imaging and densitometry analysis were performed in order to quantify the severity of the scar, however, there was significant difficulty in acquiring densitometry data. During a subsequent follow-up visit to monitor the scar, standardized room lighting and a neutral density filter were used to obtain reproducible and reliable imaging for densitometry analysis. The corneal scar was monitored over time using this standardized imaging protocol and by densitometry analysis minimal progression of the scar was evident, suggesting that recently documented significant vision loss in the left eye could not be attributed solely to changes in the scar. Conclusion and Importance: The use of a neutral density filter along with standardized ambient lighting conditions when performing Scheimpflug imaging may be necessary to reliably monitor densitometry progression of clinically severe corneal opacities.

Indexed as

Corneal scarScheimpflug imagingScleral lens

Identifiers

PMID35966118
PMCPMC9364089
OpenAlexW4289080035

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.