Evidence map›Paper›PMID 35966063›Full record

ArticleFrontiers in endocrinology2022

The correlation between transcription factor 7-like 2 gene polymorphisms and susceptibility of gestational diabetes mellitus in the population of central China: A case-control study.

Pei Zhang, Mengyao Deng, Wei Li, Qiong Dai, Hua He, Wenpei Zheng, Lu She, Bing Xiang, Jing Zeng, Feng Zhou and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. International journal of medical sciences · 2025
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Pei ZhangSchool of Public Health, Wuhan University of Science and Technology, Wuhan, China.
Mengyao DengDepartment of Clinical, Bijie Medical College, Bijie, China.
Wei LiMaternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qiong DaiMaternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hua HeMaternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wenpei ZhengMaternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lu SheSchool of Public Health, Wuhan University of Science and Technology, Wuhan, China.
Bing XiangSchool of Public Health, Wuhan University of Science and Technology, Wuhan, China.
Jing ZengSchool of Public Health, Wuhan University of Science and Technology, Wuhan, China.
Feng ZhouSchool of Public Health, Wuhan University of Science and Technology, Wuhan, China.
Yan GuoDepartment of Chronic Disease, Wuhan Centers for Disease Prevention and Control, Wuhan, China.
Mei YangSchool of Public Health, Wuhan University of Science and Technology, Wuhan, China.
Wuhan University of Science and Technology · CNHuazhong University of Science and Technology · CNBinzhou Medical University · CNWuhan Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the correlation between transcription factor 7-like 2 (TCF7L2) gene polymorphisms and gestational diabetes mellitus (GDM) risk in the central Chinese population. Methods: This case-control study examined the association of seven Results: Differences in age, pre-pregnant body mass index (BMI), and family history of type 2 diabetes mellitus (T2DM) between the case and control groups were significant ( Conclusions: The findings of this study suggested that rs4506565, rs7895340, rs7901695, and rs11196205 were the genetic susceptibility SNPs of GDM in the central Chinese population. Further studies are needed to validate our findings and clarify the underlying mechanisms.

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2Case-Control StudiesChinaFemaleHumansPolymorphism, Single NucleotidePregnancyT Cell Transcription Factor 1Transcription Factor 7-Like 2 ProteinT Cell Transcription Factor 1TCF7L2 protein, humanTranscription Factor 7-Like 2 Proteingeneticsgestational diabetes mellituspolymorphismsusceptibilitytranscription factor 7-like 2

Identifiers

PMID35966063
PMCPMC9372265
OpenAlexW4288422988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.