Evidence map›Paper›PMID 35966008›Full record

ArticleFrontiers in molecular neuroscience2022

A Deficiency of the Psychiatric Risk Gene DLG2/PSD-93 Causes Excitatory Synaptic Deficits in the Dorsolateral Striatum.

Taesun Yoo, Shambhu Joshi, Sanjaya Prajapati, Yi Sul Cho, Jinkyeong Kim, Pil-Hoon Park, Yong Chul Bae, Eunjoon Kim, Soo Young Kim

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Taesun YooCenter for Synaptic Brain Dysfunctions, Institute for Basic Science, Daejeon, South Korea.
Shambhu JoshiCollege of Pharmacy, Yeungnam University, Gyeongsan, South Korea.
Sanjaya PrajapatiCollege of Pharmacy, Yeungnam University, Gyeongsan, South Korea.
Yi Sul ChoDepartment of Anatomy and Neurobiology, School of Dentistry, Kyungpook National University, Daegu, South Korea.
Jinkyeong KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
Pil-Hoon ParkCollege of Pharmacy, Yeungnam University, Gyeongsan, South Korea.
Yong Chul BaeDepartment of Anatomy and Neurobiology, School of Dentistry, Kyungpook National University, Daegu, South Korea.
Eunjoon KimCenter for Synaptic Brain Dysfunctions, Institute for Basic Science, Daejeon, South Korea.
Soo Young KimCollege of Pharmacy, Yeungnam University, Gyeongsan, South Korea.
Yeungnam University · KRKorea Advanced Institute of Science and Technology · KRKyungpook National University · KRInstitute for Basic Science · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic variations resulting in the loss of function of the discs large homologs (DLG2)/postsynaptic density protein-93 (PSD-93) gene have been implicated in the increased risk for schizophrenia, intellectual disability, and autism spectrum disorders (ASDs). Previously, we have reported that mice lacking exon 14 of the

Indexed as

corticostriatal transmissiondorsolateral striatumMAGUKschizophrenia risk genespiny projection neurons

Identifiers

PMID35966008
PMCPMC9370999
OpenAlexW4288077471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.