Evidence map›Paper›PMID 35965986›Full record

ArticleHeliyon2022

Efficacy of methanolic extracts of some medicinal plants on wound healing in diabetic rats.

Ahmad Z Alsarayreh, Sawsan A Oran, Jumah M Shakhanbeh, Khaled M Khleifat, Yaseen T Al Qaisi, Ibrahim I Alfarrayeh, Ayah M Alkaramseh

RetractedOpen access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Parasite epidemiology and control · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. The Modulatory Effect of an Ethanolic Extract ofOxidative medicine and cellular longevity · 2024
    Article
  11. Wound Healing and Acute Dermal Toxicity Studies ofJournal of tropical medicine · 2024
    Article
4 · The record

Corrections and comments

  • Retraction · 2026-02-26Duplication of/in Image · Investigation by Journal/Publisher · Investigation by Third Party · Objections by Author(s) · Unreliable Results and/or Conclusions · · See also: https://pubpeer.com/publications/2E214C59CBD64FE1371BCF7879AF08
5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ahmad Z AlsarayrehDepartment of Biological Sciences, Faculty of Sciences, Mutah University, Al-Karak, Jordan.
Sawsan A OranDepartment of Biological Sciences, Faculty of Sciences, University of Jordan, Amman, Jordan.
Jumah M ShakhanbehDepartment of Biological Sciences, Faculty of Sciences, Mutah University, Al-Karak, Jordan.
Khaled M KhleifatFaculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman, Jordan.
Yaseen T Al QaisiDepartment of Biological Sciences, Faculty of Sciences, Mutah University, Al-Karak, Jordan.
Ibrahim I AlfarrayehDepartment of Biological Sciences, Faculty of Sciences, Mutah University, Al-Karak, Jordan.
Ayah M AlkaramsehDepartment of Biological Sciences, Faculty of Sciences, University of Jordan, Amman, Jordan.
Mutah University · JOUniversity of Jordan · JOAl-Ahliyya Amman University · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: One of the primary health concerns for diabetes individuals is wounds. The used drugs have several side effects, urging the need for new natural sources for therapeutics. Materials and methods: This study was designed to estimate the wound healing potential of the methanolic extract of Results: Plant extracts significantly increased the contraction of the wound in non-diabetic and diabetic rats (P < 0.05) and increased the fibroblast's proliferation and migration resulting in a faster healing process. The plant extracts have no cytotoxic effects. The proliferation assay exhibited the lowest cell mortality after treatment with plant extract. Conclusion: These findings may indicate that the methanolic leaf extract of the above plants can be used as new therapeutics for wound healing in diabetic patients.

Indexed as

CytotoxicityDiabetesMedicinal plantsWound healingWounds

Identifiers

PMID35965986
PMCPMC9364101
OpenAlexW4289527213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.